TY - JOUR
T1 - Effects of systemically administered cholecystokinin-octapeptide on local cerebral metabolism
AU - Lucignani, Giovanni
AU - Porrino, Linda J.
AU - Tamminga, Carol A.
PY - 1984/5/18
Y1 - 1984/5/18
N2 - The effects of systemically administered cholecystokinin-octapeptide on local cerebral glucose utilization in rats were studied by means of the 2-[14 C]deoxyglucose method. Decreases in cerebral glucose utilization were observed in discrete regions of the cerebral cortex, mesencephalon, and brainstem, including the lateral habenula, ventral tegmental area, substantia nigra pars compacta, and the nucleus of the solitary tract. These data demonstrate changes in metabolic activity in specific cerebral regions following systemic cholecystokinin administration.
AB - The effects of systemically administered cholecystokinin-octapeptide on local cerebral glucose utilization in rats were studied by means of the 2-[14 C]deoxyglucose method. Decreases in cerebral glucose utilization were observed in discrete regions of the cerebral cortex, mesencephalon, and brainstem, including the lateral habenula, ventral tegmental area, substantia nigra pars compacta, and the nucleus of the solitary tract. These data demonstrate changes in metabolic activity in specific cerebral regions following systemic cholecystokinin administration.
UR - http://www.scopus.com/inward/record.url?scp=0021136207&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0021136207&partnerID=8YFLogxK
U2 - 10.1016/0014-2999(84)90041-4
DO - 10.1016/0014-2999(84)90041-4
M3 - Article
C2 - 6086359
AN - SCOPUS:0021136207
SN - 0014-2999
VL - 101
SP - 147
EP - 151
JO - European Journal of Pharmacology
JF - European Journal of Pharmacology
IS - 1-2
ER -