Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial

Edward Abraham; Richard Wunderink; Henry Silverman; Trish M. Perl; Richard P. Wenzel; Stanley Nasraway; Howard Levy; Robert Balk; Randy Allred; James E. Pennington; Janice C. Wherry; Roger Bone

doi:10.1001/jama.1995.03520360048038

Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial

Edward Abraham, Richard Wunderink, Henry Silverman, Trish M. Perl, Richard P. Wenzel, Stanley Nasraway, Howard Levy, Robert Balk, Randy Allred, James E. Pennington, Janice C. Wherry, Roger Bone

Research output: Contribution to journal › Article › peer-review

742 Scopus citations

Original language	English (US)
Pages (from-to)	934-941
Number of pages	8
Journal	JAMA: The Journal of the American Medical Association
Volume	273
Issue number	12
DOIs	https://doi.org/10.1001/jama.1995.03520360048038
State	Published - Mar 22 1995

ASJC Scopus subject areas

Medicine(all)

Access to Document

10.1001/jama.1995.03520360048038

Cite this

Abraham, E., Wunderink, R., Silverman, H., Perl, T. M., Wenzel, R. P., Nasraway, S., Levy, H., Balk, R., Allred, R., Pennington, J. E., Wherry, J. C., & Bone, R. (1995). Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial. JAMA: The Journal of the American Medical Association, 273(12), 934-941. https://doi.org/10.1001/jama.1995.03520360048038

Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome : A Randomized, Controlled, Double-blind, Multicenter Clinical Trial. / Abraham, Edward; Wunderink, Richard; Silverman, Henry; Perl, Trish M.; Wenzel, Richard P.; Nasraway, Stanley; Levy, Howard; Balk, Robert; Allred, Randy; Pennington, James E.; Wherry, Janice C.; Bone, Roger.

In: JAMA: The Journal of the American Medical Association, Vol. 273, No. 12, 22.03.1995, p. 934-941.

Research output: Contribution to journal › Article › peer-review

Abraham, E, Wunderink, R, Silverman, H, Perl, TM, Wenzel, RP, Nasraway, S, Levy, H, Balk, R, Allred, R, Pennington, JE, Wherry, JC & Bone, R 1995, 'Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial', JAMA: The Journal of the American Medical Association, vol. 273, no. 12, pp. 934-941. https://doi.org/10.1001/jama.1995.03520360048038

Abraham E, Wunderink R, Silverman H, Perl TM, Wenzel RP, Nasraway S et al. Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial. JAMA: The Journal of the American Medical Association. 1995 Mar 22;273(12):934-941. https://doi.org/10.1001/jama.1995.03520360048038

Abraham, Edward ; Wunderink, Richard ; Silverman, Henry ; Perl, Trish M. ; Wenzel, Richard P. ; Nasraway, Stanley ; Levy, Howard ; Balk, Robert ; Allred, Randy ; Pennington, James E. ; Wherry, Janice C. ; Bone, Roger. / Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome : A Randomized, Controlled, Double-blind, Multicenter Clinical Trial. In: JAMA: The Journal of the American Medical Association. 1995 ; Vol. 273, No. 12. pp. 934-941.

@article{6e3ba1b172e141ff947ed5e3099e8089,

title = "Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial",

author = "Edward Abraham and Richard Wunderink and Henry Silverman and Perl, {Trish M.} and Wenzel, {Richard P.} and Stanley Nasraway and Howard Levy and Robert Balk and Randy Allred and Pennington, {James E.} and Wherry, {Janice C.} and Roger Bone",

year = "1995",

month = mar,

day = "22",

doi = "10.1001/jama.1995.03520360048038",

language = "English (US)",

volume = "273",

pages = "934--941",

journal = "JAMA - Journal of the American Medical Association",

issn = "0098-7484",

publisher = "American Medical Association",

number = "12",

}

TY - JOUR

T1 - Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome

T2 - A Randomized, Controlled, Double-blind, Multicenter Clinical Trial

AU - Abraham, Edward

AU - Wunderink, Richard

AU - Silverman, Henry

AU - Perl, Trish M.

AU - Wenzel, Richard P.

AU - Nasraway, Stanley

AU - Levy, Howard

AU - Balk, Robert

AU - Allred, Randy

AU - Pennington, James E.

AU - Wherry, Janice C.

AU - Bone, Roger

PY - 1995/3/22

Y1 - 1995/3/22

UR - http://www.scopus.com/inward/record.url?scp=0028957549&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028957549&partnerID=8YFLogxK

U2 - 10.1001/jama.1995.03520360048038

DO - 10.1001/jama.1995.03520360048038

M3 - Article

C2 - 7884952

AN - SCOPUS:0028957549

VL - 273

SP - 934

EP - 941

JO - JAMA - Journal of the American Medical Association

JF - JAMA - Journal of the American Medical Association

SN - 0098-7484

IS - 12

ER -

Efficacy and Safety of Monoclonal Antibody to Human Tumor Necrosis Factor α in Patients With Sepsis Syndrome: A Randomized, Controlled, Double-blind, Multicenter Clinical Trial

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this