Efficient reduction of sulfoxides with 2,6-dihydroxypyridine

Samantha J. Miller, Talia R. Collier, Weiming Wu

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

2,6-Dihydroxypyridine was found to be an efficient reagent in the deoxygenation of sulfoxides. The mild reaction conditions were compatible with functional groups such as ester and carbamate. It was also found that approximately 0.25 equivalents of 2,6-dihydroxypyridine was required for effective reduction. (C) 2000 Elsevier Science Ltd.

Original languageEnglish (US)
Pages (from-to)3781-3783
Number of pages3
JournalTetrahedron Letters
Volume41
Issue number20
DOIs
StatePublished - May 21 2000
Externally publishedYes

Keywords

  • Pyridines
  • Reduction
  • Sulfides
  • Sulfoxides

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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