Abstract
Parkinson's disease (PD) is a neurodegenerative disease in which cell loss from the midbrain substantia nigra reduces levels of the neurotransmitter dopamine. Symptoms include tremor of the hands while at rest, slowed movements, stooped posture, tendency to fall, muscular rigidity, and small handwriting. At present there is no cure for PD. Medications, neurosurgical procedures, and nonpharmacologic interventions are quite effective in controlling symptoms. While electrophysiology has a limited role at present in the diagnosis of PD, certain abnormalities are revealed on testing. These include mild background slowing of the EEG, delayed movement- related mu dropout, low amplitude sensory and motor event-related cortical potentials, and subtle autonomic impairments. These abnormalities likely reflect the neural processing deficits that cause the characteristic symptom complex.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 13-22 |
| Number of pages | 10 |
| Journal | Neurodiagnostic Journal |
| Volume | 39 |
| Issue number | 1 |
| State | Published - Mar 1999 |
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Keywords
- EEG
- Movement-related cortical potentials
- Parkinson's disease
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Neuropsychology and Physiological Psychology
- Bioengineering
- Medical Laboratory Technology
Cite this
Electrophysiologic testing in Parkinson's disease. / Arora, Anita; O'Suilleabhain, Padraig E.
In: Neurodiagnostic Journal, Vol. 39, No. 1, 03.1999, p. 13-22.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Electrophysiologic testing in Parkinson's disease
AU - Arora, Anita
AU - O'Suilleabhain, Padraig E.
PY - 1999/3
Y1 - 1999/3
N2 - Parkinson's disease (PD) is a neurodegenerative disease in which cell loss from the midbrain substantia nigra reduces levels of the neurotransmitter dopamine. Symptoms include tremor of the hands while at rest, slowed movements, stooped posture, tendency to fall, muscular rigidity, and small handwriting. At present there is no cure for PD. Medications, neurosurgical procedures, and nonpharmacologic interventions are quite effective in controlling symptoms. While electrophysiology has a limited role at present in the diagnosis of PD, certain abnormalities are revealed on testing. These include mild background slowing of the EEG, delayed movement- related mu dropout, low amplitude sensory and motor event-related cortical potentials, and subtle autonomic impairments. These abnormalities likely reflect the neural processing deficits that cause the characteristic symptom complex.
AB - Parkinson's disease (PD) is a neurodegenerative disease in which cell loss from the midbrain substantia nigra reduces levels of the neurotransmitter dopamine. Symptoms include tremor of the hands while at rest, slowed movements, stooped posture, tendency to fall, muscular rigidity, and small handwriting. At present there is no cure for PD. Medications, neurosurgical procedures, and nonpharmacologic interventions are quite effective in controlling symptoms. While electrophysiology has a limited role at present in the diagnosis of PD, certain abnormalities are revealed on testing. These include mild background slowing of the EEG, delayed movement- related mu dropout, low amplitude sensory and motor event-related cortical potentials, and subtle autonomic impairments. These abnormalities likely reflect the neural processing deficits that cause the characteristic symptom complex.
KW - EEG
KW - Movement-related cortical potentials
KW - Parkinson's disease
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UR - http://www.scopus.com/inward/citedby.url?scp=0032926242&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:0032926242
VL - 39
SP - 13
EP - 22
JO - The Neurodiagnostic journal
JF - The Neurodiagnostic journal
SN - 2164-6821
IS - 1
ER -