Elimination of the sarcoma genome from murine sarcoma virus transformed cat cells

Arthur E. Frankel, Daniel K. Haapala, Richard L. Neubauer, Peter J. Fischinger

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Cat cells transformed by Moloney murine sarcoma virus contain virus-specific sequences in their RNA and DNA. Cloned, spontaneous revenant cell lines derived from clones of these cells had no evidence of the sarcoma genome in the cell RNA or DNA as judged by RNA-complementary DNA or DNA-complementary DNA hybridizations. This is apparently the first report of loss of a transforming genome in a revertant cell line.

Original languageEnglish (US)
Pages (from-to)1264-1266
Number of pages3
JournalScience
Volume191
Issue number4233
StatePublished - 1976

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Murine Sarcoma Viruses
Sarcoma
Cats
Genome
RNA
DNA
Complementary DNA
Moloney murine sarcoma virus
Cell Line
Clone Cells
Viruses

ASJC Scopus subject areas

  • General

Cite this

Frankel, A. E., Haapala, D. K., Neubauer, R. L., & Fischinger, P. J. (1976). Elimination of the sarcoma genome from murine sarcoma virus transformed cat cells. Science, 191(4233), 1264-1266.

Elimination of the sarcoma genome from murine sarcoma virus transformed cat cells. / Frankel, Arthur E.; Haapala, Daniel K.; Neubauer, Richard L.; Fischinger, Peter J.

In: Science, Vol. 191, No. 4233, 1976, p. 1264-1266.

Research output: Contribution to journalArticle

Frankel, AE, Haapala, DK, Neubauer, RL & Fischinger, PJ 1976, 'Elimination of the sarcoma genome from murine sarcoma virus transformed cat cells', Science, vol. 191, no. 4233, pp. 1264-1266.
Frankel AE, Haapala DK, Neubauer RL, Fischinger PJ. Elimination of the sarcoma genome from murine sarcoma virus transformed cat cells. Science. 1976;191(4233):1264-1266.
Frankel, Arthur E. ; Haapala, Daniel K. ; Neubauer, Richard L. ; Fischinger, Peter J. / Elimination of the sarcoma genome from murine sarcoma virus transformed cat cells. In: Science. 1976 ; Vol. 191, No. 4233. pp. 1264-1266.
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