Embelin and its role in chronic diseases

Hong Lu, Jun Wang, Youxue Wang, Liang Qiao, Yongning Zhou

Research output: Chapter in Book/Report/Conference proceedingChapter

11 Scopus citations

Abstract

Embelia ribes Burm of Myrsinaceae family has been widely used as an herb in the traditional medicine of India. Embelin is an active component extracted from the fruits of Embelia ribes. It has a wide spectrum of biological activities and is not toxic at low dose. This review focuses on the physical–chemical properties and bioactivities of Embelin, as well as its effects on chronic diseases such as tumors, autoimmune inflammatory diseases, parasitic infections, microbial infections, diabetes, obesity, and cardio-cerebral vascular diseases. The underlying mechanisms of the effects are also discussed. As a multiple-targeted therapeutic agent, Embelin has the potential to be used widely for the treatment of a variety of chronic diseases, including malignant tumors.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages397-418
Number of pages22
DOIs
StatePublished - Sep 1 2016

Publication series

NameAdvances in Experimental Medicine and Biology
Volume928
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Anthelmintic activity
  • Anticancer activity
  • Antimicrobial activity
  • Autoimmune inflammatory diseases
  • Cardio-cerebral vascular diseases
  • Diabetes
  • Embelin

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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