Emerging use of nanoparticles for the therapeutic ablation of urologic malignancies

Joshua M. Stern, Jeffrey A Cadeddu

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Metal nanoshells are a new class of nanoparticle with highly tunable optical properties. Gold nanoshells (GNS) are particularly suitable for use in the surgical arena as their outer shell is composed of a commonly used reduced inert gold. When activated by near infrared light, GNS can raise surrounding temperatures to levels sufficient for cellular ablation. As such, investigators have established both in vitro and in vivo models to examine the role of GNS as a therapeutic modality for the thermal ablation of solid organ tumors.

Original languageEnglish (US)
Pages (from-to)93-96
Number of pages4
JournalUrologic Oncology: Seminars and Original Investigations
Volume26
Issue number1
DOIs
StatePublished - Jan 2008

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Nanoshells
Therapeutic Uses
Gold
Nanoparticles
Neoplasms
Hot Temperature
Research Personnel
Light
Temperature

Keywords

  • Gold nanoshells
  • Laser ablation
  • Nanoparticles
  • Prostate cancer

ASJC Scopus subject areas

  • Oncology
  • Urology

Cite this

Emerging use of nanoparticles for the therapeutic ablation of urologic malignancies. / Stern, Joshua M.; Cadeddu, Jeffrey A.

In: Urologic Oncology: Seminars and Original Investigations, Vol. 26, No. 1, 01.2008, p. 93-96.

Research output: Contribution to journalArticle

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