Abstract
Background: Difficulty recognizing facial emotions is an important social-cognitive deficit associated with psychotic disorders. It also may reflect a familial risk for psychosis in schizophrenia-spectrum disorders and bipolar disorder. Objective: The objectives of this study from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) consortium were to: 1) compare emotion recognition deficits in schizophrenia, schizoaffective disorder and bipolar disorder with psychosis, 2) determine the familiality of emotion recognition deficits across these disorders, and 3) evaluate emotion recognition deficits in nonpsychotic relatives with and without elevated Cluster A and Cluster B personality disorder traits. Method: Participants included probands with schizophrenia (n=. 297), schizoaffective disorder (depressed type, n=. 61; bipolar type, n=. 69), bipolar disorder with psychosis (n=. 248), their first-degree relatives (n=. 332, n=. 69, n=. 154, and n=. 286, respectively) and healthy controls (n=. 380). All participants completed the Penn Emotion Recognition Test, a standardized measure of facial emotion recognition assessing four basic emotions (happiness, sadness, anger and fear) and neutral expressions (no emotion). Results: Compared to controls, emotion recognition deficits among probands increased progressively from bipolar disorder to schizoaffective disorder to schizophrenia. Proband and relative groups showed similar deficits perceiving angry and neutral faces, whereas deficits on fearful, happy and sad faces were primarily isolated to schizophrenia probands. Even non-psychotic relatives without elevated Cluster A or Cluster B personality disorder traits showed deficits on neutral and angry faces. Emotion recognition ability was moderately familial only in schizophrenia families. Conclusions: Emotion recognition deficits are prominent but somewhat different across psychotic disorders. These deficits are reflected to a lesser extent in relatives, particularly on angry and neutral faces. Deficits were evident in non-psychotic relatives even without elevated personality disorder traits. Deficits in facial emotion recognition may reflect an important social-cognitive deficit in patients with psychotic disorders.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 105-112 |
| Number of pages | 8 |
| Journal | Schizophrenia Research |
| Volume | 158 |
| Issue number | 1-3 |
| DOIs | |
| State | Published - 2014 |
Fingerprint
Keywords
- Bipolar disorder
- Emotion recognition
- Family study
- Psychosis
- Schizoaffective disorder
- Schizophrenia
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry
Cite this
Emotion recognition deficits in schizophrenia-spectrum disorders and psychotic bipolar disorder : Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study. / Ruocco, Anthony C.; Reilly, James L.; Rubin, Leah H.; Daros, Alex R.; Gershon, Elliot S.; Tamminga, Carol A.; Pearlson, Godfrey D.; Hill, S. Kristian; Keshavan, Matcheri S.; Gur, Ruben C.; Sweeney, John A.
In: Schizophrenia Research, Vol. 158, No. 1-3, 2014, p. 105-112.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Emotion recognition deficits in schizophrenia-spectrum disorders and psychotic bipolar disorder
T2 - Findings from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) study
AU - Ruocco, Anthony C.
AU - Reilly, James L.
AU - Rubin, Leah H.
AU - Daros, Alex R.
AU - Gershon, Elliot S.
AU - Tamminga, Carol A.
AU - Pearlson, Godfrey D.
AU - Hill, S. Kristian
AU - Keshavan, Matcheri S.
AU - Gur, Ruben C.
AU - Sweeney, John A.
PY - 2014
Y1 - 2014
N2 - Background: Difficulty recognizing facial emotions is an important social-cognitive deficit associated with psychotic disorders. It also may reflect a familial risk for psychosis in schizophrenia-spectrum disorders and bipolar disorder. Objective: The objectives of this study from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) consortium were to: 1) compare emotion recognition deficits in schizophrenia, schizoaffective disorder and bipolar disorder with psychosis, 2) determine the familiality of emotion recognition deficits across these disorders, and 3) evaluate emotion recognition deficits in nonpsychotic relatives with and without elevated Cluster A and Cluster B personality disorder traits. Method: Participants included probands with schizophrenia (n=. 297), schizoaffective disorder (depressed type, n=. 61; bipolar type, n=. 69), bipolar disorder with psychosis (n=. 248), their first-degree relatives (n=. 332, n=. 69, n=. 154, and n=. 286, respectively) and healthy controls (n=. 380). All participants completed the Penn Emotion Recognition Test, a standardized measure of facial emotion recognition assessing four basic emotions (happiness, sadness, anger and fear) and neutral expressions (no emotion). Results: Compared to controls, emotion recognition deficits among probands increased progressively from bipolar disorder to schizoaffective disorder to schizophrenia. Proband and relative groups showed similar deficits perceiving angry and neutral faces, whereas deficits on fearful, happy and sad faces were primarily isolated to schizophrenia probands. Even non-psychotic relatives without elevated Cluster A or Cluster B personality disorder traits showed deficits on neutral and angry faces. Emotion recognition ability was moderately familial only in schizophrenia families. Conclusions: Emotion recognition deficits are prominent but somewhat different across psychotic disorders. These deficits are reflected to a lesser extent in relatives, particularly on angry and neutral faces. Deficits were evident in non-psychotic relatives even without elevated personality disorder traits. Deficits in facial emotion recognition may reflect an important social-cognitive deficit in patients with psychotic disorders.
AB - Background: Difficulty recognizing facial emotions is an important social-cognitive deficit associated with psychotic disorders. It also may reflect a familial risk for psychosis in schizophrenia-spectrum disorders and bipolar disorder. Objective: The objectives of this study from the Bipolar-Schizophrenia Network on Intermediate Phenotypes (B-SNIP) consortium were to: 1) compare emotion recognition deficits in schizophrenia, schizoaffective disorder and bipolar disorder with psychosis, 2) determine the familiality of emotion recognition deficits across these disorders, and 3) evaluate emotion recognition deficits in nonpsychotic relatives with and without elevated Cluster A and Cluster B personality disorder traits. Method: Participants included probands with schizophrenia (n=. 297), schizoaffective disorder (depressed type, n=. 61; bipolar type, n=. 69), bipolar disorder with psychosis (n=. 248), their first-degree relatives (n=. 332, n=. 69, n=. 154, and n=. 286, respectively) and healthy controls (n=. 380). All participants completed the Penn Emotion Recognition Test, a standardized measure of facial emotion recognition assessing four basic emotions (happiness, sadness, anger and fear) and neutral expressions (no emotion). Results: Compared to controls, emotion recognition deficits among probands increased progressively from bipolar disorder to schizoaffective disorder to schizophrenia. Proband and relative groups showed similar deficits perceiving angry and neutral faces, whereas deficits on fearful, happy and sad faces were primarily isolated to schizophrenia probands. Even non-psychotic relatives without elevated Cluster A or Cluster B personality disorder traits showed deficits on neutral and angry faces. Emotion recognition ability was moderately familial only in schizophrenia families. Conclusions: Emotion recognition deficits are prominent but somewhat different across psychotic disorders. These deficits are reflected to a lesser extent in relatives, particularly on angry and neutral faces. Deficits were evident in non-psychotic relatives even without elevated personality disorder traits. Deficits in facial emotion recognition may reflect an important social-cognitive deficit in patients with psychotic disorders.
KW - Bipolar disorder
KW - Emotion recognition
KW - Family study
KW - Psychosis
KW - Schizoaffective disorder
KW - Schizophrenia
UR - http://www.scopus.com/inward/record.url?scp=84906933641&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84906933641&partnerID=8YFLogxK
U2 - 10.1016/j.schres.2014.07.001
DO - 10.1016/j.schres.2014.07.001
M3 - Article
VL - 158
SP - 105
EP - 112
JO - Schizophrenia Research
JF - Schizophrenia Research
SN - 0920-9964
IS - 1-3
ER -