@article{72db1922c1e14870b3dedf39f61f268b,
title = "Empirical fitness landscapes reveal accessible evolutionary paths",
abstract = "When attempting to understand evolution, we traditionally rely on analysing evolutionary outcomes, despite the fact that unseen intermediates determine its course. A handful of recent studies has begun to explore these intermediate evolutionary forms, which can be reconstructed in the laboratory. With this first view on empirical evolutionary landscapes, we can now finally start asking why particular evolutionary paths are taken.",
author = "Poelwijk, {Frank J.} and Kiviet, {Daniel J.} and Weinreich, {Daniel M.} and Tans, {Sander J.}",
note = "Funding Information: Acknowledgements We thank A. Dean, D. Hartl, J. Thornton and W. Vos for critical reading of the manuscript, and S. Ta˘nase-Nicola for discussions. We thank A. Bonvin and R. Salinas for supplying the data for Fig. 2b. This work is part of the research programme of the Stichting voor Fundamenteel Onderzoek der Materie (FOM), which is financially supported by the Nederlandse Organisatie voor Wetenschappelijke Onderzoek (NWO). Copyright: Copyright 2015 Elsevier B.V., All rights reserved.",
year = "2007",
month = jan,
day = "25",
doi = "10.1038/nature05451",
language = "English (US)",
volume = "445",
pages = "383--386",
journal = "Nature",
issn = "0028-0836",
publisher = "Nature Publishing Group",
number = "7126",
}