TY - JOUR
T1 - Empirically derived patterns of pain, stooling, and incontinence and their relations to health-related quality of life among youth with chronic constipation
AU - Klages, Kimberly L.
AU - Berlin, Kristoffer S.
AU - Silverman, Alan H.
AU - Mugie, Suzanne
AU - Di Lorenzo, Carlo
AU - Nurko, Samuel
AU - Ponnambalam, Ananthasekar
AU - Sanghavi, Rina
AU - Sood, Manu R.
N1 - Publisher Copyright:
© The Author 2016.
Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2017
Y1 - 2017
N2 - Objective Chronic constipation is associated with pain, stress, and fecal incontinence, which negatively impact health-related quality of life (HRQoL); however, it is unclear if patterns of pain, stool frequency, and incontinence are differentially associated with HRQoL in youth with chronic constipation. Methods 410 caregivers completed a demographics and symptoms form, the Parental Opinions of Pediatric Constipation, Pediatric Symptom Checklist, and the Functional Disability Inventory. Results Stooling patterns were derived using Latent Variable Mixture Modeling. A three-class model emerged: withholding/avoiding (WA), pain, and fecal incontinence (FI). The pain class reported the greatest amount of disease burden/distress, greatest impairments in illness-related activity limitations, more psychosocial problems, and, along with the FI class, elevated levels of family conflict. The FI class reported the greatest amount of parental worry of social impact. Conclusions Youth with chronic constipation who experience pain or fecal incontinence may be at a greater risk for specific HRQoL problems such as illness-related activity limitations, psychosocial issues, disease burden and worry, and family conflict.
AB - Objective Chronic constipation is associated with pain, stress, and fecal incontinence, which negatively impact health-related quality of life (HRQoL); however, it is unclear if patterns of pain, stool frequency, and incontinence are differentially associated with HRQoL in youth with chronic constipation. Methods 410 caregivers completed a demographics and symptoms form, the Parental Opinions of Pediatric Constipation, Pediatric Symptom Checklist, and the Functional Disability Inventory. Results Stooling patterns were derived using Latent Variable Mixture Modeling. A three-class model emerged: withholding/avoiding (WA), pain, and fecal incontinence (FI). The pain class reported the greatest amount of disease burden/distress, greatest impairments in illness-related activity limitations, more psychosocial problems, and, along with the FI class, elevated levels of family conflict. The FI class reported the greatest amount of parental worry of social impact. Conclusions Youth with chronic constipation who experience pain or fecal incontinence may be at a greater risk for specific HRQoL problems such as illness-related activity limitations, psychosocial issues, disease burden and worry, and family conflict.
KW - Elimination disorders
KW - Gastroenterology
KW - Pain
KW - Quality of life
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U2 - 10.1093/jpepsy/jsw068
DO - 10.1093/jpepsy/jsw068
M3 - Article
C2 - 27474732
AN - SCOPUS:85018986095
SN - 0146-8693
VL - 42
SP - 325
EP - 334
JO - Journal of pediatric psychology
JF - Journal of pediatric psychology
IS - 3
ER -