Enantioselective reduction of imines catalyzed by a rhenium(V)-oxo complex

Kristine A. Nolin, Richard W. Ahn, F. Dean Toste

Research output: Contribution to journalArticlepeer-review

163 Scopus citations

Abstract

An air- and moisture-tolerant enantioselective hydrosilylation of N-phosphinyl imines employing a chiral Re(V)-oxo complex as a catalyst is described. The chiral catalyst is a cyanobis(oxazoline) (CNbox)-ligated rhenium-oxo complex of the general formula (CNbox)Re(O)Cl2(OPPh3). Using this catalyst, a wide range of aromatic imines (including cyclic, acyclic, and heteroaromatic), α-iminoesters, and α,β-unsaturated imines are reduced with good to excellent enantioselectivities.

Original languageEnglish (US)
Pages (from-to)12462-12463
Number of pages2
JournalJournal of the American Chemical Society
Volume127
Issue number36
DOIs
StatePublished - Sep 14 2005
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Fingerprint

Dive into the research topics of 'Enantioselective reduction of imines catalyzed by a rhenium(V)-oxo complex'. Together they form a unique fingerprint.

Cite this