Enantiospecific synthesis of isomeric8,9,12-trihydroxyeicosa-5(Z),10(E),14(Z)-trienoic acids

Pendri Yadagiri; Dong Soo Shin; J R Falck

doi:10.1016/S0040-4039(00)80796-0

Enantiospecific synthesis of isomeric8,9,12-trihydroxyeicosa-5(Z),10(E),14(Z)-trienoic acids

Pendri Yadagiri, Dong Soo Shin, J R Falck

Biochemistry

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Five stereoisomers of triol 2, an arachidonic acid metabolite isolated from platelets, were prepared using a convergent strategy based on β-oxido ylide homologation of a carbohydrate-derived precursor.

Original language	English (US)
Pages (from-to)	5497-5500
Number of pages	4
Journal	Tetrahedron Letters
Volume	29
Issue number	43
DOIs	https://doi.org/10.1016/S0040-4039(00)80796-0
State	Published - 1988

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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@article{8299ac8e10f14f64bf4a725f84ff17cd,

title = "Enantiospecific synthesis of isomeric8,9,12-trihydroxyeicosa-5(Z),10(E),14(Z)-trienoic acids",

abstract = "Five stereoisomers of triol 2, an arachidonic acid metabolite isolated from platelets, were prepared using a convergent strategy based on β-oxido ylide homologation of a carbohydrate-derived precursor.",

author = "Pendri Yadagiri and Shin, {Dong Soo} and Falck, {J R}",

note = "Funding Information: Supported financially Foundation (I-7821, for his generous by grants from the USPHS NIH (GM 312781, the and NATO (RC SS/OOZS). The authors thank Dr. advice throughout the project.",

year = "1988",

doi = "10.1016/S0040-4039(00)80796-0",

language = "English (US)",

volume = "29",

pages = "5497--5500",

journal = "Tetrahedron Letters",

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T1 - Enantiospecific synthesis of isomeric8,9,12-trihydroxyeicosa-5(Z),10(E),14(Z)-trienoic acids

AU - Yadagiri, Pendri

AU - Shin, Dong Soo

AU - Falck, J R

N1 - Funding Information: Supported financially Foundation (I-7821, for his generous by grants from the USPHS NIH (GM 312781, the and NATO (RC SS/OOZS). The authors thank Dr. advice throughout the project.

PY - 1988

Y1 - 1988

N2 - Five stereoisomers of triol 2, an arachidonic acid metabolite isolated from platelets, were prepared using a convergent strategy based on β-oxido ylide homologation of a carbohydrate-derived precursor.

AB - Five stereoisomers of triol 2, an arachidonic acid metabolite isolated from platelets, were prepared using a convergent strategy based on β-oxido ylide homologation of a carbohydrate-derived precursor.

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U2 - 10.1016/S0040-4039(00)80796-0

DO - 10.1016/S0040-4039(00)80796-0

M3 - Article

AN - SCOPUS:0023697009

SN - 0040-4039

VL - 29

SP - 5497

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 43

ER -

Enantiospecific synthesis of isomeric8,9,12-trihydroxyeicosa-5(Z),10(E),14(Z)-trienoic acids

Abstract

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