Enantiospecific synthesis of isomeric8,9,12-trihydroxyeicosa-5(Z),10(E),14(Z)-trienoic acids

Pendri Yadagiri, Dong Soo Shin, J R Falck

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Five stereoisomers of triol 2, an arachidonic acid metabolite isolated from platelets, were prepared using a convergent strategy based on β-oxido ylide homologation of a carbohydrate-derived precursor.

Original languageEnglish (US)
Pages (from-to)5497-5500
Number of pages4
JournalTetrahedron Letters
Volume29
Issue number43
DOIs
StatePublished - 1988

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Stereoisomerism
Metabolites
Platelets
Arachidonic Acid
Blood Platelets
Carbohydrates
Acids

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Enantiospecific synthesis of isomeric8,9,12-trihydroxyeicosa-5(Z),10(E),14(Z)-trienoic acids. / Yadagiri, Pendri; Shin, Dong Soo; Falck, J R.

In: Tetrahedron Letters, Vol. 29, No. 43, 1988, p. 5497-5500.

Research output: Contribution to journalArticle

Yadagiri, Pendri ; Shin, Dong Soo ; Falck, J R. / Enantiospecific synthesis of isomeric8,9,12-trihydroxyeicosa-5(Z),10(E),14(Z)-trienoic acids. In: Tetrahedron Letters. 1988 ; Vol. 29, No. 43. pp. 5497-5500.
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