Enantiospecific synthesis of methyl 11,12- and 14,15-epoxyeicosatrienoate

J R Falck, Sukumar Manna, Jorge Capdevila

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

The methyl esters of the cytochrome P-450 epoxygenase metabolites 11(S),12(R)-and 14(R),15(S)-epoxyeicosatrienoic acid and some analogues were prepared enantiospecifically from 15(S)-HETE derived precursors.

Original languageEnglish (US)
Pages (from-to)2443-2446
Number of pages4
JournalTetrahedron Letters
Volume25
Issue number23
DOIs
StatePublished - 1984

Fingerprint

Hydroxyeicosatetraenoic Acids
Metabolites
Cytochrome P-450 Enzyme System
Esters
Acids
15-hydroxy-5,8,11,13-eicosatetraenoic acid
14,15-epoxy-5,8,11-eicosatrienoic acid

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Enantiospecific synthesis of methyl 11,12- and 14,15-epoxyeicosatrienoate. / Falck, J R; Manna, Sukumar; Capdevila, Jorge.

In: Tetrahedron Letters, Vol. 25, No. 23, 1984, p. 2443-2446.

Research output: Contribution to journalArticle

Falck, J R ; Manna, Sukumar ; Capdevila, Jorge. / Enantiospecific synthesis of methyl 11,12- and 14,15-epoxyeicosatrienoate. In: Tetrahedron Letters. 1984 ; Vol. 25, No. 23. pp. 2443-2446.
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