Enantiospecific total synthesis of a novel arachidonic acid metabolite 3-hydroxyeicosatetraenoic acid

R. K. Bhatt, J R Falck, S. Nigam

Research output: Contribution to journalArticle

31 Scopus citations

Abstract

The enantiomers R- and S-3-hydroxyeicosatetraenoic acid 11a, 11b were synthesized from coupling of a chiral aldehyde 7 with a Wittig salt 4, which were derived from 2-deoxy-D-ribose and arachidonic acid, respectively.

Original languageEnglish (US)
Pages (from-to)249-252
Number of pages4
JournalTetrahedron Letters
Volume39
Issue number3-4
DOIs
StatePublished - Jan 15 1998

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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