Energy Regulation: HIF MXIes It Up with the C-MYC Powerhouse

Patrick D. Sutphin, Amato J. Giaccia, Denise A. Chan

Research output: Contribution to journalArticle

14 Scopus citations


The phenomenon of aerobic glycolysis observed in cancer cells has remained unexplained. In the May 2007 issue of Cancer Cell, Zhang and colleagues determine that the hypoxia-inducible factor family of transcriptional factors regulate mitochondrial biogenesis through inhibition of C-MYC.

Original languageEnglish (US)
Pages (from-to)845-846
Number of pages2
JournalDevelopmental Cell
Issue number6
Publication statusPublished - Jun 5 2007


ASJC Scopus subject areas

  • Developmental Biology

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