Enzymatic activity of naturally occurring 1-acylglycerol-3-phosphate-O- acyltransferase 2 mutants associated with congenital generalized lipodystrophy

Medicine & Life Sciences

• 1-Acylglycerol-3-Phosphate O-Acyltransferase 100%
• Congenital Generalized Lipodystrophy 82%
• lysophosphatidic acid 19%
• Phosphatidic Acids 19%
• oleoyl-coenzyme A 12%
• alpha-glycerophosphoric acid 10%
• Glycerophospholipids 10%
• Acyltransferases 10%
• Acylation 9%
• Enzymes 7%
• Cricetulus 7%
• Ovary 6%
• Adipose Tissue 6%
• Triglycerides 5%
• Proteins 5%
• Amino Acids 5%
• Phenotype 4%
• Mutation 4%
• Genes 2%

Chemical Compounds

• Enzyme Activity 41%
• Lysophosphatidic Acid 25%
• Phosphatidic Acid 21%
• Glycerophospholipid 11%
• Triglyceride 8%
• Acylation 8%
• Mutation 7%
• Biosynthesis 7%
• Protein 6%
• Reduction 3%
• Acid 2%