Eosinophilic lung disease associated with non-Hodgkin lymphoma: A case report and review of the literature

Research output: Contribution to journalArticle

Abstract

Eosinophilic lung diseases have many causes but are not often the result of neoplastic disease. We describe a patient with subacute dyspnea due to eosinophilic lung disease who also had a peripheral T-cell lymphoma. The diagnosis was made by imaging and transbronchial biopsies of the lungs along with an excisional biopsy of a palpable epitrochlear lymph node. There is a rare association between eosinophilic pneumonias and non-Hodgkin lymphomas. This is the third known case of a peripheral T-cell lymphoma associated with eosinophilic lung disease. This report highlights the association, discusses theorized mechanisms involved, and emphasizes the importance of searching for underlying etiologies for eosinophilic lung disease.

Original languageEnglish (US)
Pages (from-to)13-16
Number of pages4
JournalClinical Pulmonary Medicine
Volume14
Issue number1
DOIs
StatePublished - Jan 2007

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Non-Hodgkin's Lymphoma
Lung Diseases
Peripheral T-Cell Lymphoma
Pulmonary Eosinophilia
Biopsy
Dyspnea
Lymph Nodes
Lung

Keywords

  • Eosinophilic lung disease
  • Eosinophilic pneumonia
  • IL-5
  • Non-Hodgkin lymphoma

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

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abstract = "Eosinophilic lung diseases have many causes but are not often the result of neoplastic disease. We describe a patient with subacute dyspnea due to eosinophilic lung disease who also had a peripheral T-cell lymphoma. The diagnosis was made by imaging and transbronchial biopsies of the lungs along with an excisional biopsy of a palpable epitrochlear lymph node. There is a rare association between eosinophilic pneumonias and non-Hodgkin lymphomas. This is the third known case of a peripheral T-cell lymphoma associated with eosinophilic lung disease. This report highlights the association, discusses theorized mechanisms involved, and emphasizes the importance of searching for underlying etiologies for eosinophilic lung disease.",
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AB - Eosinophilic lung diseases have many causes but are not often the result of neoplastic disease. We describe a patient with subacute dyspnea due to eosinophilic lung disease who also had a peripheral T-cell lymphoma. The diagnosis was made by imaging and transbronchial biopsies of the lungs along with an excisional biopsy of a palpable epitrochlear lymph node. There is a rare association between eosinophilic pneumonias and non-Hodgkin lymphomas. This is the third known case of a peripheral T-cell lymphoma associated with eosinophilic lung disease. This report highlights the association, discusses theorized mechanisms involved, and emphasizes the importance of searching for underlying etiologies for eosinophilic lung disease.

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