Ephective endocytosis

Michael M. Halford, Michael J. Chumley, Mark Henkemeyer

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Two important new reports identify endocytosis of EphB-ephrinB complexes as a mechanism for switching between cell-cell adhesion and repulsion following plasma membrane contact. Together with the previously described shedding of ephrinA following EphA engagement, these findings resolve the paradox of how an adhesive receptor-ligand interaction generates a repulsive cellular response.

Original languageEnglish (US)
Pages (from-to)536-537
Number of pages2
JournalDevelopmental Cell
Volume5
Issue number4
DOIs
StatePublished - Oct 1 2003

Fingerprint

Cell adhesion
Cell membranes
Endocytosis
Cell Adhesion
Adhesives
Cell Membrane
Ligands

ASJC Scopus subject areas

  • Developmental Biology

Cite this

Ephective endocytosis. / Halford, Michael M.; Chumley, Michael J.; Henkemeyer, Mark.

In: Developmental Cell, Vol. 5, No. 4, 01.10.2003, p. 536-537.

Research output: Contribution to journalArticle

Halford, Michael M. ; Chumley, Michael J. ; Henkemeyer, Mark. / Ephective endocytosis. In: Developmental Cell. 2003 ; Vol. 5, No. 4. pp. 536-537.
@article{96afbc7ca6b240f08c89dc60c5453d46,
title = "Ephective endocytosis",
abstract = "Two important new reports identify endocytosis of EphB-ephrinB complexes as a mechanism for switching between cell-cell adhesion and repulsion following plasma membrane contact. Together with the previously described shedding of ephrinA following EphA engagement, these findings resolve the paradox of how an adhesive receptor-ligand interaction generates a repulsive cellular response.",
author = "Halford, {Michael M.} and Chumley, {Michael J.} and Mark Henkemeyer",
year = "2003",
month = "10",
day = "1",
doi = "10.1016/S1534-5807(03)00299-5",
language = "English (US)",
volume = "5",
pages = "536--537",
journal = "Developmental Cell",
issn = "1534-5807",
publisher = "Cell Press",
number = "4",

}

TY - JOUR

T1 - Ephective endocytosis

AU - Halford, Michael M.

AU - Chumley, Michael J.

AU - Henkemeyer, Mark

PY - 2003/10/1

Y1 - 2003/10/1

N2 - Two important new reports identify endocytosis of EphB-ephrinB complexes as a mechanism for switching between cell-cell adhesion and repulsion following plasma membrane contact. Together with the previously described shedding of ephrinA following EphA engagement, these findings resolve the paradox of how an adhesive receptor-ligand interaction generates a repulsive cellular response.

AB - Two important new reports identify endocytosis of EphB-ephrinB complexes as a mechanism for switching between cell-cell adhesion and repulsion following plasma membrane contact. Together with the previously described shedding of ephrinA following EphA engagement, these findings resolve the paradox of how an adhesive receptor-ligand interaction generates a repulsive cellular response.

UR - http://www.scopus.com/inward/record.url?scp=0141989900&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0141989900&partnerID=8YFLogxK

U2 - 10.1016/S1534-5807(03)00299-5

DO - 10.1016/S1534-5807(03)00299-5

M3 - Article

C2 - 14536055

AN - SCOPUS:0141989900

VL - 5

SP - 536

EP - 537

JO - Developmental Cell

JF - Developmental Cell

SN - 1534-5807

IS - 4

ER -