Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions

J. Capdevila; G. D. Snijder; J R Falck

doi:10.1016/0014-5793(84)80625-0

Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions

J. Capdevila, G. D. Snijder, J R Falck

Biochemistry

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

Microsomal fractions isolated from rat anterior pituitary glands catalyze the oxygenation of arachidonic acid. By a combination of Chromatographic and mass spectrometric techniques, we have identified epoxy-eicosatrienoic acids as reaction products and thus documented the presence of an NADPH-dependent arachidonic acid epoxygenase activity in rat adenohypophysis.

Original language	English (US)
Pages (from-to)	319-322
Number of pages	4
Journal	FEBS Letters
Volume	178
Issue number	2
DOIs	https://doi.org/10.1016/0014-5793(84)80625-0
State	Published - Dec 10 1984

Keywords

Anterior pituitary
Arachidonic acid
Epoxyeicosatrienoic acid
Epoxygenase

ASJC Scopus subject areas

Biophysics
Structural Biology
Biochemistry
Molecular Biology
Genetics
Cell Biology

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10.1016/0014-5793(84)80625-0

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title = "Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions",

abstract = "Microsomal fractions isolated from rat anterior pituitary glands catalyze the oxygenation of arachidonic acid. By a combination of Chromatographic and mass spectrometric techniques, we have identified epoxy-eicosatrienoic acids as reaction products and thus documented the presence of an NADPH-dependent arachidonic acid epoxygenase activity in rat adenohypophysis.",

keywords = "Anterior pituitary, Arachidonic acid, Epoxyeicosatrienoic acid, Epoxygenase",

author = "J. Capdevila and Snijder, {G. D.} and Falck, {J R}",

note = "Funding Information: Supported in part by grants NIGMS 16488,H D15465a nd 31278.",

year = "1984",

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doi = "10.1016/0014-5793(84)80625-0",

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T1 - Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions

AU - Capdevila, J.

AU - Snijder, G. D.

AU - Falck, J R

N1 - Funding Information: Supported in part by grants NIGMS 16488,H D15465a nd 31278.

PY - 1984/12/10

Y1 - 1984/12/10

N2 - Microsomal fractions isolated from rat anterior pituitary glands catalyze the oxygenation of arachidonic acid. By a combination of Chromatographic and mass spectrometric techniques, we have identified epoxy-eicosatrienoic acids as reaction products and thus documented the presence of an NADPH-dependent arachidonic acid epoxygenase activity in rat adenohypophysis.

AB - Microsomal fractions isolated from rat anterior pituitary glands catalyze the oxygenation of arachidonic acid. By a combination of Chromatographic and mass spectrometric techniques, we have identified epoxy-eicosatrienoic acids as reaction products and thus documented the presence of an NADPH-dependent arachidonic acid epoxygenase activity in rat adenohypophysis.

KW - Anterior pituitary

KW - Arachidonic acid

KW - Epoxyeicosatrienoic acid

KW - Epoxygenase

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JF - FEBS Letters

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ER -

Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions

Abstract

Keywords

ASJC Scopus subject areas

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