Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions

J. Capdevila, G. D. Snijder, J R Falck

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Microsomal fractions isolated from rat anterior pituitary glands catalyze the oxygenation of arachidonic acid. By a combination of Chromatographic and mass spectrometric techniques, we have identified epoxy-eicosatrienoic acids as reaction products and thus documented the presence of an NADPH-dependent arachidonic acid epoxygenase activity in rat adenohypophysis.

Original languageEnglish (US)
Pages (from-to)319-322
Number of pages4
JournalFEBS Letters
Volume178
Issue number2
DOIs
StatePublished - Dec 10 1984

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Anterior Pituitary Gland
Arachidonic Acid
Rats
Oxygenation
Reaction products
Acids
arachidonate epoxygenase

Keywords

  • Anterior pituitary
  • Arachidonic acid
  • Epoxyeicosatrienoic acid
  • Epoxygenase

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology

Cite this

Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions. / Capdevila, J.; Snijder, G. D.; Falck, J R.

In: FEBS Letters, Vol. 178, No. 2, 10.12.1984, p. 319-322.

Research output: Contribution to journalArticle

Capdevila, J. ; Snijder, G. D. ; Falck, J R. / Epoxygenation of arachidonic acid by rat anterior pituitary microsomal fractions. In: FEBS Letters. 1984 ; Vol. 178, No. 2. pp. 319-322.
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