Eruptive xanthomas masquerading as molluscum contagiosum

Jennifer Sorrell, Heather Salvaggio, Abhimanyu Garg, Lulu Guo, Stephen C. Duck, Amy S. Paller

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Eruptive xanthomas are cutaneous manifestations of hyperlipidemias in which lipids accumulate in large foam cells within the skin. They classically present as crops of 1- to 4-mm yellow-orange papules and are often associated with extreme hypertriglyceridemia. We describe a 12-year-old boy with autism who was thought to have widespread molluscum contagiosum for a year before dermatologic consultation was obtained. Recognition of eruptive xanthomas led to the discovery of massive hypertriglyceridemia (serum triglycerides 6853 mg/dL) and diabetes mellitus. Through medical intervention, including insulin and fenofibrate therapy, and dietary modi fication with weight loss, the xanthomas cleared during the subsequent months, and his serum triglyceride levels nearly normalized.

Original languageEnglish (US)
JournalPediatrics
Volume134
Issue number1
DOIs
StatePublished - 2014

Fingerprint

Molluscum Contagiosum
Xanthomatosis
Hypertriglyceridemia
Triglycerides
Fenofibrate
Skin Manifestations
Foam Cells
Autistic Disorder
Hyperlipidemias
Serum
Weight Loss
Diabetes Mellitus
Referral and Consultation
Insulin
Lipids
Skin
Manifestation
Therapy
Mollusca
Boys

Keywords

  • Autism
  • Behavior eating
  • BMI
  • Dermatology

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Arts and Humanities (miscellaneous)

Cite this

Sorrell, J., Salvaggio, H., Garg, A., Guo, L., Duck, S. C., & Paller, A. S. (2014). Eruptive xanthomas masquerading as molluscum contagiosum. Pediatrics, 134(1). https://doi.org/10.1542/peds.2013-2108

Eruptive xanthomas masquerading as molluscum contagiosum. / Sorrell, Jennifer; Salvaggio, Heather; Garg, Abhimanyu; Guo, Lulu; Duck, Stephen C.; Paller, Amy S.

In: Pediatrics, Vol. 134, No. 1, 2014.

Research output: Contribution to journalArticle

Sorrell, J, Salvaggio, H, Garg, A, Guo, L, Duck, SC & Paller, AS 2014, 'Eruptive xanthomas masquerading as molluscum contagiosum', Pediatrics, vol. 134, no. 1. https://doi.org/10.1542/peds.2013-2108
Sorrell, Jennifer ; Salvaggio, Heather ; Garg, Abhimanyu ; Guo, Lulu ; Duck, Stephen C. ; Paller, Amy S. / Eruptive xanthomas masquerading as molluscum contagiosum. In: Pediatrics. 2014 ; Vol. 134, No. 1.
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