Ethnic Disparities in Early-Onset Gastric Cancer: A Population-Based Study in Texas and California

Background: Incidence rates of gastric cancer are increasing in Results: Of 3,047 persons diagnosed with EOGC, 73.2% were young adults (age <50 years), particularly among Hispanic persons. Hispanic White. Incidence rates were 1.29 [95% confidence interval We estimated incidence rates of early-onset gastric cancer (EOGC) (CI), 1.24–1.35] and 0.31 (95% CI, 0.29–0.33) per 100,000 Hispanic among Hispanic and non-Hispanic White persons by census tract White and non-Hispanic White persons, respectively, with consispoverty level and county-level metro/nonmetro residence. tently higher incidence rates among Hispanic persons at all levels of Methods: We used population-based data from the California poverty. There were no statistically significant associations between and Texas Cancer Registries from 1995 to 2016 to estimate age-ethnicity and distant stage diagnosis in adjusted analysis. adjusted incidence rates of EOGC among Hispanic and non-Conclusions: There are ethnic disparities in EOGC incidence Hispanic White persons by year, sex, tumor stage, census tract rates that persist across poverty levels. poverty level, metro versus nonmetro county, and state. We used Impact: EOGC incidence rates vary by ethnicity and poverty; logistic regression models to identify factors associated with distant these factors should be considered when assessing disease risk and stage diagnosis. targeting prevention efforts.