Evaluating tumor-suppressor gene combinations news-and-views

Research output: Contribution to journalShort survey

Abstract

In vivo verification of tumor suppressors and their interactions with each other has required complex experiments. A report in this issue uses a novel CRISPR-Cas9 technology with barcodes to test, in parallel, the tumorigenic potential of functional loss of multiple tumor-suppressor genes in the context of a genetically engineered mouse model of lung adenocarcinoma with mutant Kras.

Original languageEnglish (US)
Pages (from-to)480-482
Number of pages3
JournalNature Genetics
Volume50
Issue number4
DOIs
StatePublished - Apr 1 2018

ASJC Scopus subject areas

  • Genetics

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