Evidence of resilience: Neuroimaging in former prisoners of war

Thomas Freeman, Tim Kimbrell, Leroy Booe, Michael Myers, David Cardwell, Diana M. Lindquist, John Hart, Richard A. Komoroski

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

In this study, single voxel proton magnetic resonance spectroscopic imaging (1H-MRS) and volumetric analysis of hippocampal magnetic resonance imaging (MRI) images were used to determine if any differences in hippocampal biochemistry or volume were present between former prisoners of war (POWs) with and without posttraumatic stress disorder (PTSD) and control subjects matched for age and education. This study did not find lower hippocampal concentrations of N-acetylaspartate (NAA), smaller hippocampal volumes, or more impaired memory function in older veterans with PTSD compared with a group matched for traumatic experience or a nontraumatized control group.

Original languageEnglish (US)
Pages (from-to)59-64
Number of pages6
JournalPsychiatry Research - Neuroimaging
Volume146
Issue number1
DOIs
StatePublished - Jan 30 2006

Keywords

  • Hippocampus
  • Magnetic resonance spectroscopy
  • N-acetylaspartate
  • Posttraumatic stress disorder

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Psychiatry and Mental health

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    Freeman, T., Kimbrell, T., Booe, L., Myers, M., Cardwell, D., Lindquist, D. M., Hart, J., & Komoroski, R. A. (2006). Evidence of resilience: Neuroimaging in former prisoners of war. Psychiatry Research - Neuroimaging, 146(1), 59-64. https://doi.org/10.1016/j.pscychresns.2005.07.007