TY - JOUR
T1 - Executive functioning and the metabolic syndrome
T2 - A project FRONTIER study
AU - Falkowski, Jed
AU - Atchison, Timothy
AU - Debutte-Smith, Maxine
AU - Weiner, Myron F.
AU - O'Bryant, Sid
N1 - Funding Information:
This work was supported by the National Institute on Aging of the National Institutes of Health (R01AG039389 and P30AG12300). This study was also supported in part by grants from the Texas Council on Alzheimer’s Disease and Related Disorders, the Hogg Foundation for Mental Health (JRG-040 and JRG-149), the Environmental Protection Agency (RD834794), and the National Academy of Neuropsychology. Funding for this project was provided by the Texas Tech University Health Sciences Center F. Marie Hall Institute for Rural and Community Health, Garrison Institute on Aging, Laura W. Bush Institute for Women’s Health, and Department of Neurology.
PY - 2014/2
Y1 - 2014/2
N2 - Decrements in cognitive functioning have been linked to the metabolic syndrome (MetS), a risk factor for cardiovascular disease defined by the presence of three of the following: elevated blood pressure, increased waist circumference, elevated blood glucose, elevated triglycerides, and low high-density lipoprotein cholesterol. We examined the relationship between four measures of executive functioning (EF) and MetS as diagnosed by National Heart, Lung, and Blood Institute-American Heart Association criteria. MetS was examined in a rural population of 395 persons with a mean age of 61.3 years, 71.4% women, 37.0% Hispanic, 53.7% White non-Hispanic. There was a 61.0% prevalence of MetS. We derived a factor score from the four executive function measures which was used to compare those with and without the syndrome, as well as any additive effects of components of the syndrome. Those with MetS exhibited significantly poorer performance than those without the syndrome. However, there was no additive effect, having more components of the syndrome was not related to lower performance. The presence of MetS was associated with poorer EF in this rural cohort of community dwelling volunteers.
AB - Decrements in cognitive functioning have been linked to the metabolic syndrome (MetS), a risk factor for cardiovascular disease defined by the presence of three of the following: elevated blood pressure, increased waist circumference, elevated blood glucose, elevated triglycerides, and low high-density lipoprotein cholesterol. We examined the relationship between four measures of executive functioning (EF) and MetS as diagnosed by National Heart, Lung, and Blood Institute-American Heart Association criteria. MetS was examined in a rural population of 395 persons with a mean age of 61.3 years, 71.4% women, 37.0% Hispanic, 53.7% White non-Hispanic. There was a 61.0% prevalence of MetS. We derived a factor score from the four executive function measures which was used to compare those with and without the syndrome, as well as any additive effects of components of the syndrome. Those with MetS exhibited significantly poorer performance than those without the syndrome. However, there was no additive effect, having more components of the syndrome was not related to lower performance. The presence of MetS was associated with poorer EF in this rural cohort of community dwelling volunteers.
KW - Cardiovascular risk factors
KW - Executive functioning
KW - Metabolic syndrome
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U2 - 10.1093/arclin/act078
DO - 10.1093/arclin/act078
M3 - Article
C2 - 24152591
AN - SCOPUS:84893150940
SN - 0887-6177
VL - 29
SP - 47
EP - 53
JO - Archives of Clinical Neuropsychology
JF - Archives of Clinical Neuropsychology
IS - 1
ER -