Experience with various techniques for the refinement of protein structures

J. Deisenhofer, S. J. Remington, W. Steigemann

Research output: Contribution to journalArticle

19 Scopus citations


The following main advantages of the Jack-Levitt method became apparent during the refinement of the above-mentioned structures: refinement at low resolution is possible, geometric restraints can be relaxed temporarily, treatment of branched chains is easy, the method requires about 30% less computing time than Diamond's real space refinement, distorted geometry can be repaired, and refinement of temperature factors at 2.9 Å resolution is possible.

Original languageEnglish (US)
Pages (from-to)303-323
Number of pages21
JournalMethods in Enzymology
VolumeVOL. 115
Publication statusPublished - 1985


ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology

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