Experimental observation of acoustic emissions generated by a pulsed proton beam from a hospital-based clinical cyclotron

Kevin C. Jones, François Vander Stappen, Christopher R. Bawiec, Guillaume Janssens, Peter A. Lewin, Damien Prieels, Timothy D. Solberg, Chandra M. Sehgal, Stephen Avery

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Purpose: To measure the acoustic signal generated by a pulsed proton spill from a hospital-based clinical cyclotron. Methods: An electronic function generator modulated the IBA C230 isochronous cyclotron to create a pulsed proton beam. The acoustic emissions generated by the proton beam were measured in water using a hydrophone. The acoustic measurements were repeated with increasing proton current and increasing distance between detector and beam. Results: The cyclotron generated proton spills with rise times of 18 μs and a maximum measured instantaneous proton current of 790 nA. Acoustic emissions generated by the proton energy deposition were measured to be on the order of mPa. The origin of the acoustic wave was identified as the proton beam based on the correlation between acoustic emission arrival time and distance between the hydrophone and proton beam. The acoustic frequency spectrum peaked at 10 kHz, and the acoustic pressure amplitude increased monotonically with increasing proton current. Conclusions: The authors report the first observation of acoustic emissions generated by a proton beam from a hospital-based clinical cyclotron. When modulated by an electronic function generator, the cyclotron is capable of creating proton spills with fast rise times (18 μs) and high instantaneous currents (790 nA). Measurements of the proton-generated acoustic emissions in a clinical setting may provide a method for in vivo proton range verification and patient monitoring.

Original languageEnglish (US)
Pages (from-to)7090-7097
Number of pages8
JournalMedical Physics
Volume42
Issue number12
DOIs
StatePublished - Dec 1 2015

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Cyclotrons
Acoustics
Protons
Observation
Physiologic Monitoring

Keywords

  • acoustic pulses
  • monitoring of dose distribution
  • pulsed proton beam
  • radiation therapy
  • range verification

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

Jones, K. C., Vander Stappen, F., Bawiec, C. R., Janssens, G., Lewin, P. A., Prieels, D., ... Avery, S. (2015). Experimental observation of acoustic emissions generated by a pulsed proton beam from a hospital-based clinical cyclotron. Medical Physics, 42(12), 7090-7097. https://doi.org/10.1118/1.4935865

Experimental observation of acoustic emissions generated by a pulsed proton beam from a hospital-based clinical cyclotron. / Jones, Kevin C.; Vander Stappen, François; Bawiec, Christopher R.; Janssens, Guillaume; Lewin, Peter A.; Prieels, Damien; Solberg, Timothy D.; Sehgal, Chandra M.; Avery, Stephen.

In: Medical Physics, Vol. 42, No. 12, 01.12.2015, p. 7090-7097.

Research output: Contribution to journalArticle

Jones, KC, Vander Stappen, F, Bawiec, CR, Janssens, G, Lewin, PA, Prieels, D, Solberg, TD, Sehgal, CM & Avery, S 2015, 'Experimental observation of acoustic emissions generated by a pulsed proton beam from a hospital-based clinical cyclotron', Medical Physics, vol. 42, no. 12, pp. 7090-7097. https://doi.org/10.1118/1.4935865
Jones, Kevin C. ; Vander Stappen, François ; Bawiec, Christopher R. ; Janssens, Guillaume ; Lewin, Peter A. ; Prieels, Damien ; Solberg, Timothy D. ; Sehgal, Chandra M. ; Avery, Stephen. / Experimental observation of acoustic emissions generated by a pulsed proton beam from a hospital-based clinical cyclotron. In: Medical Physics. 2015 ; Vol. 42, No. 12. pp. 7090-7097.
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