The presence of Na butyrate in cultures of chick embryo myoblasts interferes with normal differentiation of these cells. At a concentration of 3 mM it reversibly inhibits the formation of myotubes without affecting the normal program of biochemical differentiation. This effect is not related to the inhibition of cell growth produced by the same concentration of butyrate but may be due to modifications of the cell membranes by the drug.
ASJC Scopus subject areas
- Cell Biology