Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis

David Sassoon, Gary Lyons, Woodring E. Wright, Victor Lin, Andrew Lassar, Harold Weintraub, Margaret Buckingham

Research output: Contribution to journalArticle

470 Citations (Scopus)

Abstract

MyoDl and myogenin are muscle-specific proteins which can convert non-myogenic cells in culture to differentiated muscle fibres, implicating them in myogenic determination. The pattern of expression of MyoDl and myogenin during the early stages of muscle formation in the mouse embryo in vivo and in limb-bud explants cultured in vitro, indicates that they may have different functions in different types of muscle during development.

Original languageEnglish (US)
Pages (from-to)303-307
Number of pages5
JournalNature
Volume341
Issue number6240
StatePublished - 1989

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Myogenic Regulatory Factors
Myogenin
Embryonic Development
Limb Buds
Muscles
Muscle Development
Muscle Proteins
Embryonic Structures
Cell Culture Techniques

ASJC Scopus subject areas

  • General

Cite this

Sassoon, D., Lyons, G., Wright, W. E., Lin, V., Lassar, A., Weintraub, H., & Buckingham, M. (1989). Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis. Nature, 341(6240), 303-307.

Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis. / Sassoon, David; Lyons, Gary; Wright, Woodring E.; Lin, Victor; Lassar, Andrew; Weintraub, Harold; Buckingham, Margaret.

In: Nature, Vol. 341, No. 6240, 1989, p. 303-307.

Research output: Contribution to journalArticle

Sassoon, D, Lyons, G, Wright, WE, Lin, V, Lassar, A, Weintraub, H & Buckingham, M 1989, 'Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis', Nature, vol. 341, no. 6240, pp. 303-307.
Sassoon D, Lyons G, Wright WE, Lin V, Lassar A, Weintraub H et al. Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis. Nature. 1989;341(6240):303-307.
Sassoon, David ; Lyons, Gary ; Wright, Woodring E. ; Lin, Victor ; Lassar, Andrew ; Weintraub, Harold ; Buckingham, Margaret. / Expression of two myogenic regulatory factors myogenin and MyoDl during mouse embryogenesis. In: Nature. 1989 ; Vol. 341, No. 6240. pp. 303-307.
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