TY - JOUR
T1 - External validity of the pediatric cardiac quality of life inventory
AU - Marino, Bradley S.
AU - Drotar, Dennis
AU - Cassedy, Amy
AU - Davis, Richard
AU - Tomlinson, Ryan S.
AU - Mellion, Katelyn
AU - Mussatto, Kathleen
AU - Mahony, Lynn
AU - Newburger, Jane W.
AU - Tong, Elizabeth
AU - Cohen, Mitchell I.
AU - Helfaer, Mark A.
AU - Kazak, Anne E.
AU - Wray, Jo
AU - Wernovsky, Gil
AU - Shea, Judy A.
AU - Ittenbach, Richard
PY - 2011/3
Y1 - 2011/3
N2 - Purpose: The Pediatric Cardiac Quality of Life Inventory (PCQLI) is a disease-specific, health-related quality of life (HRQOL) measure for pediatric heart disease (HD). The purpose of this study was to demonstrate the external validity of PCQLI scores. Methods: The PCQLI development site (Development sample) and six geographically diverse centers in the United States (Composite sample) recruited pediatric patients with acquired or congenital HD. Item response option variability, scores [Total (TS); Disease Impact (DI) and Psychosocial Impact (PI) subscales], patterns of correlation, and internal consistency were compared between samples. Results: A total of 3,128 patients and parent participants (1,113 Development; 2,015 Composite) were analyzed. Response option variability patterns of all items in both samples were acceptable. Inter-sample score comparisons revealed no differences. Median item-total (Development, 0.57; Composite, 0.59) and item-subscale (Development, DI 0.58, PI 0.59; Composite, DI 0.58, PI 0.56) correlations were moderate. Subscale-subscale (0.79 for both samples) and subscale-total (Development, DI 0.95, PI 0.95; Composite, DI 0.95, PI 0.94) correlations and internal consistency (Development, TS 0.93, DI 0.90, PI 0.84; Composite, TS 0.93, DI 0.89, PI 0.85) were high in both samples. Conclusion: PCQLI scores are externally valid across the US pediatric HD population and may be used for multi-center HRQOL studies.
AB - Purpose: The Pediatric Cardiac Quality of Life Inventory (PCQLI) is a disease-specific, health-related quality of life (HRQOL) measure for pediatric heart disease (HD). The purpose of this study was to demonstrate the external validity of PCQLI scores. Methods: The PCQLI development site (Development sample) and six geographically diverse centers in the United States (Composite sample) recruited pediatric patients with acquired or congenital HD. Item response option variability, scores [Total (TS); Disease Impact (DI) and Psychosocial Impact (PI) subscales], patterns of correlation, and internal consistency were compared between samples. Results: A total of 3,128 patients and parent participants (1,113 Development; 2,015 Composite) were analyzed. Response option variability patterns of all items in both samples were acceptable. Inter-sample score comparisons revealed no differences. Median item-total (Development, 0.57; Composite, 0.59) and item-subscale (Development, DI 0.58, PI 0.59; Composite, DI 0.58, PI 0.56) correlations were moderate. Subscale-subscale (0.79 for both samples) and subscale-total (Development, DI 0.95, PI 0.95; Composite, DI 0.95, PI 0.94) correlations and internal consistency (Development, TS 0.93, DI 0.90, PI 0.84; Composite, TS 0.93, DI 0.89, PI 0.85) were high in both samples. Conclusion: PCQLI scores are externally valid across the US pediatric HD population and may be used for multi-center HRQOL studies.
KW - Acquired heart disease
KW - Congenital heart disease
KW - External validity
KW - Health-related quality of life
KW - Pediatrics
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U2 - 10.1007/s11136-010-9731-4
DO - 10.1007/s11136-010-9731-4
M3 - Article
C2 - 21188538
AN - SCOPUS:79952251265
SN - 0962-9343
VL - 20
SP - 205
EP - 214
JO - Quality of Life Research
JF - Quality of Life Research
IS - 2
ER -