Extrapancreatic neural plexus invasion by pancreatic carcinoma: Characteristics on magnetic resonance imaging

Xiao Ming Zhang, Donald G. Mitchell, Agnes Witkiewicz, Sachit Verma, Diane Bergin

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Background: Our objective is to study the characteristics of extrapancreatic neural plexus invasion by pancreatic carcinoma on MR imaging. Methods: 20 patients with both pancreatic carcinoma and extrapancreatic neural plexus invasion confirmed by pathology were recruited in this study. MR imaging was performed within 1 month before surgery. On MR images, signal intensity at the site of potential extrapancreatic neural plexus invasion, lymph nodes and tumor size were noted. The relationship of extrapancreatic neural plexus invasion to these findings was analyzed. Results: Signs of extrapancreatic neural plexus invasion were depicted on MR imaging in 80% of patients, which included streaky and strand-like signal intensity structure in fat tissue in 50% of patients and irregular masses adjacent to tumor in 30%. Signal intensity at invasion site was similar to that of pancreatic carcinoma. The frequencies of patients with vascular invasion and with lymph nodes larger than 5 mm were, respectively, 50% and 55%. Tumor diameter was 24 ± 7 mm on MR imaging. Extrapancreatic neural plexus invasion was correlated with vascular invasion (r = 0.58, P < 0.005), slightly related with lymphadenopathy (r = 0.35, 0.1 > P > 0.05), but not related with tumor size. Conclusion: MR imaging is useful to depict extrapancreatic neural plexus invasion by pancreatic carcinoma.

Original languageEnglish (US)
Pages (from-to)634-641
Number of pages8
JournalAbdominal Imaging
Volume34
Issue number5
DOIs
StatePublished - Sep 1 2009

Keywords

  • Carcinoma
  • Extrapancreatic neural plexus
  • Invasion
  • Magnetic resonance
  • Pancreas

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Gastroenterology
  • Urology

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