Extubation during pediatric extracorporeal membrane oxygenation: A single-center experience

Pilar Anton-Martin, Marita T. Thompson, Paul D. Sheeran, Anne C. Fischer, Donna Taylor, James A. Thomas

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Objectives: Describe aspects of one center's experience extubating infants and children during extracorporeal membrane oxygenation.

Design: Retrospective review of medical records.

Setting: Seventy-one-bed critical care service (PICU and cardiovascular ICU) in a large urban tertiary children's hospital.

Patients: Pediatric and neonatal patients supported on extracorporeal membrane oxygenation between 1996 and 2013 who were either not intubated or extubated greater than 24 hours during their extracorporeal membrane oxygenation course.

Interventions: None.

Measurements and Main Results: Sixteen of 511 patients on extracorporeal membrane oxygenation were extubated for at least 24 hours during their extracorporeal membrane oxygenation courses. Fourteen had respiratory failure and two had cardiac disease. Five patients died while on extracorporeal membrane oxygenation, but the cause of death was not related to complications associated with extubation. Extubated patients were supported a median of 19.7 days on extracorporeal membrane oxygenation, with a median extubation latency (time between cannulation and first extubation) of 6.2 days and a median extubation duration of 5.5 days. Mean time extubated was 43% of the total time on extracorporeal membrane oxygenation. Two patients were reintubated briefly or had a laryngeal mask airway placed for decannulation (n = 1). The remaining patients were extubated within 5 days of decannulation, weeks afterward (n = 2), transferred to outside facilities (n = 2), or died during extracorporeal membrane oxygenation support (n = 5). We also observed no complications directly attributable to extubation and spontaneous reaeration of consolidated lungs in acute respiratory distress syndrome in extubated patients on extracorporeal membrane oxygenation.

Conclusion: Extubation and discontinuation of mechanical ventilation appear feasible in patients requiring long-term extracorporeal membrane oxygenation. Emergency procedure planning may need to be modified in extubated patients on extracorporeal membrane oxygenation.

Original languageEnglish (US)
Pages (from-to)861-869
Number of pages9
JournalPediatric Critical Care Medicine
Volume15
Issue number9
DOIs
StatePublished - Nov 10 2014

Fingerprint

Extracorporeal Membrane Oxygenation
Pediatrics
Laryngeal Masks
Urban Hospitals
Adult Respiratory Distress Syndrome
Critical Care
Artificial Respiration
Tertiary Care Centers
Catheterization
Respiratory Insufficiency
Medical Records
Cause of Death
Heart Diseases
Emergencies

Keywords

  • Extracorporeal membrane life support
  • Extracorporeal membrane oxygenation
  • Extubation
  • Mechanical ventilation
  • Ventilator-induced lung injury

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Critical Care and Intensive Care Medicine

Cite this

Anton-Martin, P., Thompson, M. T., Sheeran, P. D., Fischer, A. C., Taylor, D., & Thomas, J. A. (2014). Extubation during pediatric extracorporeal membrane oxygenation: A single-center experience. Pediatric Critical Care Medicine, 15(9), 861-869. https://doi.org/10.1097/PCC.0000000000000235

Extubation during pediatric extracorporeal membrane oxygenation : A single-center experience. / Anton-Martin, Pilar; Thompson, Marita T.; Sheeran, Paul D.; Fischer, Anne C.; Taylor, Donna; Thomas, James A.

In: Pediatric Critical Care Medicine, Vol. 15, No. 9, 10.11.2014, p. 861-869.

Research output: Contribution to journalArticle

Anton-Martin, P, Thompson, MT, Sheeran, PD, Fischer, AC, Taylor, D & Thomas, JA 2014, 'Extubation during pediatric extracorporeal membrane oxygenation: A single-center experience', Pediatric Critical Care Medicine, vol. 15, no. 9, pp. 861-869. https://doi.org/10.1097/PCC.0000000000000235
Anton-Martin, Pilar ; Thompson, Marita T. ; Sheeran, Paul D. ; Fischer, Anne C. ; Taylor, Donna ; Thomas, James A. / Extubation during pediatric extracorporeal membrane oxygenation : A single-center experience. In: Pediatric Critical Care Medicine. 2014 ; Vol. 15, No. 9. pp. 861-869.
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