Eyelid Necrosis and Secondary Cicatrical Ectropion Secondary to Levamisole-Associated Vasculitis

Sathyadeepak Ramesh, Deepak Sobti, Ronald Mancini

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 56-year-old female presented with eyelid necrosis secondary to systemic levamisole-induced vasculitis. Skin biopsy revealed necrotic epidermis with small-vessel thrombosis, fibrinoid reaction, and neutrophilic infiltration of vessel walls in the dermis with +pANCA. She was treated with plasmapheresis and steroids. Six months later, she developed severe, symptomatic cicatrical ectropion with marked anterior lamellar shortage and middle lamellar contracture. Scar release in the middle lamellar plane with lateral tarsal strip procedures was performed, with full-thickness skin grafts from the upper eyelids. She remained fully epithelialized postoperatively with improvement in symptoms, although she incomplete graft take due to her eyelid necrosis and compromised dermal blood supply.

Original languageEnglish (US)
JournalOphthalmic Plastic and Reconstructive Surgery
DOIs
StateAccepted/In press - Sep 21 2015

Fingerprint

Ectropion
Levamisole
Eyelids
Vasculitis
Necrosis
Skin
Transplants
Plasmapheresis
Contracture
Dermis
Epidermis
Cicatrix
Thrombosis
Steroids
Biopsy

ASJC Scopus subject areas

  • Ophthalmology
  • Surgery

Cite this

Eyelid Necrosis and Secondary Cicatrical Ectropion Secondary to Levamisole-Associated Vasculitis. / Ramesh, Sathyadeepak; Sobti, Deepak; Mancini, Ronald.

In: Ophthalmic Plastic and Reconstructive Surgery, 21.09.2015.

Research output: Contribution to journalArticle

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