Fabrication of an oriented lectin microarray

Daniel C. Propheter, Ku Lung Hsu, Lara K. Mahal

Research output: Contribution to journalArticle

24 Scopus citations

Abstract

To tag or not to tag: An oriented lectin microarray utilizing recombinant lectins with the standard prokaryotic expression tag glutathione S-transferase has been reported. The oriented lectin microarray improves the overall sensitivity and limits of detection by site-specific orientation of recombinant lectins. This continual improvement of the lectin microarray technology enables a deeper understanding of the biological function of glycans. (Figure Presented)

Original languageEnglish (US)
Pages (from-to)1203-1207+1157
JournalChemBioChem
Volume11
Issue number9
DOIs
StatePublished - Jun 14 2010

Keywords

  • Carbohydrates
  • GST-tagged proteins
  • Glycomics
  • Microarrays
  • Recombinant lectin

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Organic Chemistry

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