Fabrication of an oriented lectin microarray

Daniel C. Propheter, Ku Lung Hsu, Lara K. Mahal

Research output: Contribution to journalArticle

23 Scopus citations

Abstract

To tag or not to tag: An oriented lectin microarray utilizing recombinant lectins with the standard prokaryotic expression tag glutathione S-transferase has been reported. The oriented lectin microarray improves the overall sensitivity and limits of detection by site-specific orientation of recombinant lectins. This continual improvement of the lectin microarray technology enables a deeper understanding of the biological function of glycans. (Figure Presented)

Original languageEnglish (US)
JournalChemBioChem
Volume11
Issue number9
DOIs
Publication statusPublished - Jun 14 2010

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Keywords

  • Carbohydrates
  • Glycomics
  • GST-tagged proteins
  • Microarrays
  • Recombinant lectin

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Molecular Medicine
  • Molecular Biology
  • Medicine(all)

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