A method for cultivating intact foetal mouse hearts in vitro has been developed. The hearts survive and beat rhythmically and spontaneously for 3 weeks or more under appropriate cultural conditions. Prolonged function is promoted by atmospheres containing greater than 20% O2 and by media supplemented with serum, insulin and cortisol.
ASJC Scopus subject areas
- Molecular Biology
- Cardiology and Cardiovascular Medicine