TY - JOUR
T1 - Failure of single-dose lecithin to alter aspects of central cholinergic activity in Alzheimer's disease
AU - Pomara, N.
AU - Domino, E. F.
AU - Yoon, H.
AU - Brinkman, S.
AU - Tamminga, C. A.
AU - Gershon, S.
PY - 1983/10/6
Y1 - 1983/10/6
N2 - The effect of a single dose (15 g/70 kg) of lecithin (95% phosphatidylcholine) on several measures of central cholinergic activity (memory, cortisol, prolactin, pulse, blood pressure) was assessed in individuals with Alzheimer's disease. In contrast to the reported effects of physostigmine, a cholinesterase inhibitor, lecithin had no effect on these parameters, despite significant increases in plasma and erythrocyte choline.
AB - The effect of a single dose (15 g/70 kg) of lecithin (95% phosphatidylcholine) on several measures of central cholinergic activity (memory, cortisol, prolactin, pulse, blood pressure) was assessed in individuals with Alzheimer's disease. In contrast to the reported effects of physostigmine, a cholinesterase inhibitor, lecithin had no effect on these parameters, despite significant increases in plasma and erythrocyte choline.
UR - http://www.scopus.com/inward/record.url?scp=0020598925&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020598925&partnerID=8YFLogxK
M3 - Article
C2 - 6874650
AN - SCOPUS:0020598925
SN - 0160-6689
VL - 44
SP - 293
EP - 295
JO - Journal of Clinical Psychiatry
JF - Journal of Clinical Psychiatry
IS - 8 I
ER -