Familial Alzheimer's disease mutations in presenilins: Effects on endoplasmic reticulum calcium homeostasis and correlation with clinical phenotypes

Medicine & Life Sciences

• Presenilins 100%
• Endoplasmic Reticulum 66%
• Alzheimer Disease 53%
• Homeostasis 50%
• Calcium 47%
• Phenotype 41%
• Mutation 38%
• Amyloid Precursor Protein Secretases 17%
• Presenilin-2 10%
• Spastic Paraparesis 10%
• Presenilin-1 9%
• Wool 9%
• Amyloid beta-Protein Precursor 8%
• Knockout Mice 6%
• Catalytic Domain 6%
• Exons 5%
• Fibroblasts 5%
• Genes 2%

Social Sciences

• dementia 69%
• experiment 9%
• physical disability 8%
• agricultural product 8%