Familial clustering of atrial fibrillation and comparative longitudinal outcomes of familial and non-familial atrial fibrillation

Anna Gundlund, Jonas B. Olesen, Eric D. Peterson, Gunnar H. Gislason, Emil L. Fosbøl

Research output: Contribution to journalReview articlepeer-review

Abstract

Several studies have suggested that family history of atrial fibrillation (AF) is an important risk factor for AF, with several specific genetic regions now implicated through Genome Wide Association Studies. In addition, familial AF is associated with earlier age of onset and affects patients with fewer comorbid conditions than their non-familial counterparts. While those with familial AF have worse symptoms, all-cause mortality and risk of thromboembolic complications are similar among familial and non-familial AF patients.

Original languageEnglish (US)
Pages (from-to)257-263
Number of pages7
JournalJournal of Comparative Effectiveness Research
Volume6
Issue number3
DOIs
StatePublished - May 2017
Externally publishedYes

Keywords

  • arrhythmia
  • clinical outcomes
  • family history

ASJC Scopus subject areas

  • Health Policy

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