Abstract
We now understand the biochemical basis of this disorder, which affects one person in 500 in the United States. It is inherited as an autosomal dominant or quasi-dominant trait, with phenotypic effects expressed in heterozygotes as well as in homozygotes. Diagnosis is possible at birth, but effective treatment is thus far available only for the heterozygous form.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 35-46 |
| Number of pages | 12 |
| Journal | Hospital Practice |
| Volume | 20 |
| Issue number | 11 |
| State | Published - 1985 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
Familial hypercholesterolemia : A genetic receptor disease. / Goldstein, J. L.; Brown, M. S.
In: Hospital Practice, Vol. 20, No. 11, 1985, p. 35-46.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Familial hypercholesterolemia
T2 - A genetic receptor disease
AU - Goldstein, J. L.
AU - Brown, M. S.
PY - 1985
Y1 - 1985
N2 - We now understand the biochemical basis of this disorder, which affects one person in 500 in the United States. It is inherited as an autosomal dominant or quasi-dominant trait, with phenotypic effects expressed in heterozygotes as well as in homozygotes. Diagnosis is possible at birth, but effective treatment is thus far available only for the heterozygous form.
AB - We now understand the biochemical basis of this disorder, which affects one person in 500 in the United States. It is inherited as an autosomal dominant or quasi-dominant trait, with phenotypic effects expressed in heterozygotes as well as in homozygotes. Diagnosis is possible at birth, but effective treatment is thus far available only for the heterozygous form.
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UR - http://www.scopus.com/inward/citedby.url?scp=0022355074&partnerID=8YFLogxK
M3 - Article
C2 - 3932389
AN - SCOPUS:0022355074
VL - 20
SP - 35
EP - 46
JO - Hospital practice (1995)
JF - Hospital practice (1995)
SN - 2154-8331
IS - 11
ER -