Familial pseudomembranous colitis and its relation to lincomycin therapy

Mary Jo E Harrod, Michael S. Brown, Arthur G. Weinberg, William N. Harkness, Joseph L. Goldstein

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Severe pseudomembranous colitis was observed in 3 members of a single family: the father and 2 of his children. 2 of the affected family members received the antibiotic lincomycin prior to the onset of their symptoms. The findings in this family raise the possibility that antibiotic-induced pseudomembranous colitis in some patients may be the result of a pharmacogenetic interaction.

Original languageEnglish (US)
Pages (from-to)808-812
Number of pages5
JournalThe American Journal of Digestive Diseases
Volume20
Issue number9
DOIs
StatePublished - Sep 1975

Fingerprint

Pseudomembranous Enterocolitis
Lincomycin
Anti-Bacterial Agents
Pharmacogenetics
Fathers
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology
  • Medicine(all)

Cite this

Familial pseudomembranous colitis and its relation to lincomycin therapy. / Harrod, Mary Jo E; Brown, Michael S.; Weinberg, Arthur G.; Harkness, William N.; Goldstein, Joseph L.

In: The American Journal of Digestive Diseases, Vol. 20, No. 9, 09.1975, p. 808-812.

Research output: Contribution to journalArticle

Harrod, Mary Jo E ; Brown, Michael S. ; Weinberg, Arthur G. ; Harkness, William N. ; Goldstein, Joseph L. / Familial pseudomembranous colitis and its relation to lincomycin therapy. In: The American Journal of Digestive Diseases. 1975 ; Vol. 20, No. 9. pp. 808-812.
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