Familial pseudomembranous colitis and its relation to lincomycin therapy

Mary Jo E Harrod, Michael S. Brown, Arthur G. Weinberg, William N. Harkness, Joseph L. Goldstein

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Severe pseudomembranous colitis was observed in 3 members of a single family: the father and 2 of his children. 2 of the affected family members received the antibiotic lincomycin prior to the onset of their symptoms. The findings in this family raise the possibility that antibiotic-induced pseudomembranous colitis in some patients may be the result of a pharmacogenetic interaction.

Original languageEnglish (US)
Pages (from-to)808-812
Number of pages5
JournalThe American Journal of Digestive Diseases
Volume20
Issue number9
DOIs
StatePublished - Sep 1 1975

ASJC Scopus subject areas

  • Gastroenterology

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