@article{8594a6e6ba0c4d8d8d77b7703376885a,
title = "Family discord is associated with increased substance use for pregnant substance users",
abstract = "Childhood abuse and partner violence are associated with prenatal substance abuse, but the potential impact of current family discord, which reflects broader family relationships and encompasses problems less severe than violence, has had little evaluation in pregnant substance users. Using data from 196 pregnant substance users participating in a NIDA Clinical Trials Network randomized clinical trial, we examined the relationship of baseline family discord to substance use and treatment session attendance. Family discord was assessed using items from the family composite of the Addiction Severity Index. Substance use was assessed by the Substance Use Calendar and urine drug screens (UDS). Assessments were weekly for four weeks and at two- and four-month post-randomization. Women with family discord were more likely to report living with a problematic substance user, reported a higher percentage of substance use days throughout each study phase, had a greater proportion of positive UDS over the four-month study period, and attended more weeks of treatment during the first month. Specific treatment interventions targeting pregnant women with family discord may be warranted.",
keywords = "Family discord, Pregnancy, Substance use, Treatment engagement",
author = "Denton, {Wayne H.} and Adinoff, {Bryon H.} and Daniel Lewis and Robrina Walker and Theresa Winhusen",
note = "Funding Information: Bryon H. Adinoff received grant support from NIAAA, NIDA, and the Department of Veterans Affairs; consulted for Teva Pharmaceutical Industries Ltd., Shook, Hardy & Bacon LLP (medical malpractice for tobacco companies), and Paul J. Passante, P.C. (medical malpractice); and received honoraria from the Medical University of South Carolina, American Instititute of Biological Sciences (AIBS), American Academy of Addiction Psychiatry, Methodist Medical Center (Dallas, TX), Vanderbilt University, John Peter Smith Hospital, University of North Texas Health Science Center; American Academy of Addiction Psychiatry, and the University of New Mexico. Wayne H. Denton, Theresa Winhusen, Daniel Lewis, and Robrina Walker declare that they have no conflicts of interest. The authors alone are responsible for the content and writing of the article. Funding Information: This study was supported by a series of grants from NIDA as part of the Cooperative Agreement on National Drug Abuse Treatment Clinical Trials Network (CTN) in the Ohio Valley Node (U10DA013732), the North Carolina Node (U10DA013711), the Southwest Node (U10DA015833), and the Texas node (U10DA020024). NIDA had no further role in study design or in the collection, analysis, and interpretation of data. NIDA Center for the Clinical Trials Network (CCTN) personnel contributed to the design of the original study and CCTN contractors played a role in the collection and analysis of the data from the original study. NIDA had no further role in the design of this analysis, in the manuscript writing of the report, or in the decision to submit the paper for publication. Approval from the NIDA CTN Publications Committee was required in order to proceed with submission, but this committee primarily consists of independent scientists rather than NIDA personnel.",
year = "2014",
month = feb,
doi = "10.3109/10826084.2013.840002",
language = "English (US)",
volume = "49",
pages = "326--332",
journal = "Substance Use and Misuse",
issn = "1082-6084",
publisher = "Informa Healthcare",
number = "3",
}