Family history of glaucoma as a prognostic factor in primary open angle glaucoma

D. Wang, J. T. Whitson, R. R. Allingham, D. D. McIntire

Research output: Contribution to journalArticle

Abstract

Purpose. To assess family history of glaucoma as a prognostic factor in primary open angle glaucoma (POAG). Methods. A group of 19 patients presenting with a diagnosis of POAG who had a family history of glaucoma, were aged 55 years or older, and had no history of diabetes mellitus, systemic hypertension, cardiovascular disease, or cerebral vascular disease were followed for an average of 61 months. A similar group of 21 POAG patients with no family history of glaucoma was used as a control. Results. Patients with family history of glaucoma had an increased incidence of loss of one or more lines of snellen visual acuity (48% vs 26%, P<0.02), deterioration of visual field (60% vs 50%, P < 0.39), need for argon laser trabeculoplasty (40% vs 16%%, P < 0.02) or filtration surgery (29% vs 11%, P < 0.03) and were more likely to require multiple glaucoma medications for control of their disease (74% vs 58%, P<0.03). Conclusion. Our results suggest that family history of glaucoma may identify a group of POAG patients who have a poorer prognosis from their disease and should be treated earlier and more aggressively.

Original languageEnglish (US)
JournalInvestigative Ophthalmology and Visual Science
Volume37
Issue number3
StatePublished - Feb 15 1996

Fingerprint

Glaucoma
Filtering Surgery
Trabeculectomy
Argon
Visual Fields
Vascular Diseases
Visual Acuity
Primary Open Angle Glaucoma
Diabetes Mellitus
Lasers
Cardiovascular Diseases
Hypertension
Incidence

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Family history of glaucoma as a prognostic factor in primary open angle glaucoma. / Wang, D.; Whitson, J. T.; Allingham, R. R.; McIntire, D. D.

In: Investigative Ophthalmology and Visual Science, Vol. 37, No. 3, 15.02.1996.

Research output: Contribution to journalArticle

@article{eec2d8bf0626474db9271c37e2374a12,
title = "Family history of glaucoma as a prognostic factor in primary open angle glaucoma",
abstract = "Purpose. To assess family history of glaucoma as a prognostic factor in primary open angle glaucoma (POAG). Methods. A group of 19 patients presenting with a diagnosis of POAG who had a family history of glaucoma, were aged 55 years or older, and had no history of diabetes mellitus, systemic hypertension, cardiovascular disease, or cerebral vascular disease were followed for an average of 61 months. A similar group of 21 POAG patients with no family history of glaucoma was used as a control. Results. Patients with family history of glaucoma had an increased incidence of loss of one or more lines of snellen visual acuity (48{\%} vs 26{\%}, P<0.02), deterioration of visual field (60{\%} vs 50{\%}, P < 0.39), need for argon laser trabeculoplasty (40{\%} vs 16{\%}{\%}, P < 0.02) or filtration surgery (29{\%} vs 11{\%}, P < 0.03) and were more likely to require multiple glaucoma medications for control of their disease (74{\%} vs 58{\%}, P<0.03). Conclusion. Our results suggest that family history of glaucoma may identify a group of POAG patients who have a poorer prognosis from their disease and should be treated earlier and more aggressively.",
author = "D. Wang and Whitson, {J. T.} and Allingham, {R. R.} and McIntire, {D. D.}",
year = "1996",
month = "2",
day = "15",
language = "English (US)",
volume = "37",
journal = "Investigative Ophthalmology and Visual Science",
issn = "0146-0404",
publisher = "Association for Research in Vision and Ophthalmology Inc.",
number = "3",

}

TY - JOUR

T1 - Family history of glaucoma as a prognostic factor in primary open angle glaucoma

AU - Wang, D.

AU - Whitson, J. T.

AU - Allingham, R. R.

AU - McIntire, D. D.

PY - 1996/2/15

Y1 - 1996/2/15

N2 - Purpose. To assess family history of glaucoma as a prognostic factor in primary open angle glaucoma (POAG). Methods. A group of 19 patients presenting with a diagnosis of POAG who had a family history of glaucoma, were aged 55 years or older, and had no history of diabetes mellitus, systemic hypertension, cardiovascular disease, or cerebral vascular disease were followed for an average of 61 months. A similar group of 21 POAG patients with no family history of glaucoma was used as a control. Results. Patients with family history of glaucoma had an increased incidence of loss of one or more lines of snellen visual acuity (48% vs 26%, P<0.02), deterioration of visual field (60% vs 50%, P < 0.39), need for argon laser trabeculoplasty (40% vs 16%%, P < 0.02) or filtration surgery (29% vs 11%, P < 0.03) and were more likely to require multiple glaucoma medications for control of their disease (74% vs 58%, P<0.03). Conclusion. Our results suggest that family history of glaucoma may identify a group of POAG patients who have a poorer prognosis from their disease and should be treated earlier and more aggressively.

AB - Purpose. To assess family history of glaucoma as a prognostic factor in primary open angle glaucoma (POAG). Methods. A group of 19 patients presenting with a diagnosis of POAG who had a family history of glaucoma, were aged 55 years or older, and had no history of diabetes mellitus, systemic hypertension, cardiovascular disease, or cerebral vascular disease were followed for an average of 61 months. A similar group of 21 POAG patients with no family history of glaucoma was used as a control. Results. Patients with family history of glaucoma had an increased incidence of loss of one or more lines of snellen visual acuity (48% vs 26%, P<0.02), deterioration of visual field (60% vs 50%, P < 0.39), need for argon laser trabeculoplasty (40% vs 16%%, P < 0.02) or filtration surgery (29% vs 11%, P < 0.03) and were more likely to require multiple glaucoma medications for control of their disease (74% vs 58%, P<0.03). Conclusion. Our results suggest that family history of glaucoma may identify a group of POAG patients who have a poorer prognosis from their disease and should be treated earlier and more aggressively.

UR - http://www.scopus.com/inward/record.url?scp=33750198719&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33750198719&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:33750198719

VL - 37

JO - Investigative Ophthalmology and Visual Science

JF - Investigative Ophthalmology and Visual Science

SN - 0146-0404

IS - 3

ER -