Fast imaging of phosphocreatine using a RARE pulse sequence

Robert L. Greenman, Mark A. Elliott, Krista Vandenborne, Mitchell D. Schnall, Robert E. Lenkinski

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

A technique is described for acquiring phosphocreatine (PCr) images of skeletal muscle using a rapid acquisition with relaxation enhancement (RARE) pulse sequence. All of the phosphorus metabolites other than PCr are forced to dephase within the first few echoes, whereas the Carr-Purcell Meiboom- Gill (CPMG) pulse sequence maintains a high PCr signal long enough to acquire 64 echoes in a single shot. Axial PCr images of a human forearm with a signal-to-noise ratio of 9 were acquired in 2 min. The effect of the refocusing pulse seotion profile on the ratio of desired to undesired metabolite signal is demonstrated.

Original languageEnglish (US)
Pages (from-to)851-854
Number of pages4
JournalMagnetic resonance in medicine
Volume39
Issue number5
DOIs
StatePublished - May 1 1998

Keywords

  • Multiecho sequence
  • Phosphorus Imaging
  • RARE

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Greenman, R. L., Elliott, M. A., Vandenborne, K., Schnall, M. D., & Lenkinski, R. E. (1998). Fast imaging of phosphocreatine using a RARE pulse sequence. Magnetic resonance in medicine, 39(5), 851-854. https://doi.org/10.1002/mrm.1910390523