Fast-track cardiac anesthesia: Use of remifentanil combined with intrathecal morphine as an alternative to sufentanil during desflurane anesthesia

Eduardo Zarate, Paige Latham, Paul F. White, Robert Bossard, Lisa Morse, Linda K. Douning, Chen Shi, Lei Chi

Research output: Contribution to journalArticle

64 Scopus citations

Abstract

The purpose of this cardiac fast-track study was to evaluate the use of remifentanil (R) combined with intrathecal (IT) morphine as an alternative to sufentanil (S) during desflurane anesthesia with respect to postoperative pain control. Prior to entering the operating room, patients in the R group (n = 20) received morphine, 8 μg/kg IT. Anesthesia was induced using a standardized anesthetic technique in all patients. In the R group, anesthesia was maintained with R, 0.1 μg·kg-1·min-1 in combination with desflurane 3-10%. In the S group (n = 20), patients received S 0.3 μg·kg-1·h-1 and desflurane 3-10%. There were no differences between the two groups with respect to time from arrival in the intensive care unit to tracheal extubation (5.1 ± 4.3 h vs 5.8 ± 6.7 h for R and S groups, respectively). After extubation, patients in the R group had significantly lower visual analog pain scores, reduced patient-controlled analgesic requirements, and greater satisfaction with their perioperative pain management, compared with patients in the S group. We conclude that R combined with IT morphine provided superior pain control after cardiac surgery compared with a S-based general anesthetic technique.

Original languageEnglish (US)
Pages (from-to)283-287
Number of pages5
JournalAnesthesia and analgesia
Volume91
Issue number2
DOIs
StatePublished - Jan 1 2000

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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