Fatigue in Multiple Sclerosis

Research output: Contribution to journalReview articlepeer-review

27 Scopus citations


Multiple sclerosis is a chronic, debilitating, inflammatory, and neurodegenerative disease of the central nervous system. There is no cure for the disease, and its management includes use of symptomatic agents and diseasemodifying therapies to reduce and/or prevent relapses and disease progression. Fatigue affects up to 90% of MS patients and can significantly impair function, quality of life, and interaction with family and friends. The common causes of fatigue and effective interventions and treatments are reviewed in this article.

Original languageEnglish (US)
Pages (from-to)363-372
Number of pages10
JournalPhysical Medicine and Rehabilitation Clinics of North America
Issue number2
StatePublished - May 2009


  • Fatigue
  • Human
  • Multiple sclerosis
  • Neurorehabilitation
  • Quality of life
  • Treatment of fatigue

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation


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