Feasibility and Short-Term Effects of a Multi-Component Emergency Department Blood Pressure Intervention: A Pilot Randomized Trial

Andrew J. Spieker, Lyndsay A. Nelson, Russell L. Rothman, Christianne L. Roumie, Sunil Kripalani, Joseph Coco, Daniel Fabbri, Phillip Levy, Sean P. Collins, Tommy Wang, Dandan Liu, Candace D. McNaughton

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

BACKGROUND: Emergency department (ED) visits can be opportunities to address uncontrolled hypertension. We sought to compare short-term blood pressure measures between the Vanderbilt Emergency Room Bundle (VERB) intervention and usual care plus education. METHODS AND RESULTS: We conducted a randomized trial of 206 adult patients with hypertension and elevated systolic blood pressure (SBP) presenting to 2 urban emergency departments in Tennessee, USA. The VERB intervention included educational materials, a brief motivational interview, pillbox, primary care engagement letter, pharmacy resources, and 45 days of informational and reminder text messages. The education arm received a hypertension pamphlet. After 78 participants were enrolled, text messages requested confirmation of receipt. The primary clinical outcome was 30-day SBP. The median 30-day SBP was 122 and 126 mm Hg in the VERB and education arms, respectively. We estimated the mean 30-day SBP to be 3.98 mm Hg lower in the VERB arm (95% CI, −2.44 to 10.4; P=0.22). Among participants enrolled after text messages were adapted, the respective median SBPs were 121 and 130 mm Hg, and we estimated the mean 30-day SBP to be 8.57 mm Hg lower in the VERB arm (95% CI, 0.98‒­16.2; P=0.027). In this subgroup, the median response rate to VERB text messages was 56% (interquartile range, [26%‒­80%]). CONCLUSIONS: This pilot study demonstrated feasibility and found an improvement in SBP for the subgroup for whom interactive messages were featured. Future studies should evaluate the role of interactive text messaging as part of a comprehensive emergency department intervention to improve blood pressure control.

Original languageEnglish (US)
Article numbere024339
JournalJournal of the American Heart Association
Volume11
Issue number5
DOIs
StatePublished - Mar 1 2022

Keywords

  • emergency care
  • hypertension
  • medication adherence
  • motivational interviewing
  • patient engagement

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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