Felbamate urolithiasis

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Purpose: To report a case of felbamate (FBM) urolithiasis. Methods: Urographic imaging [sonography, abdominal computed tomography (CT), intravenous pyelogram, voiding cystourethrogram] and urologic procedures (cystoscopy with lithotripsy, ureteral stent) to define and capture the stones. Stone identification was by infrared spectroscopy and gas chromatography/mass spectrometry. Results: A 15-year-old boy had painful hematuria, bilateral ureteral obstruction, and urinary retention. Kidney, bladder, and ureteral stones were found, and ureteral stent placement was required to relieve obstruction. The stone material was identified as FBM by chemical analysis. Stone formation ceased with discontinuation of FBM. Conclusions: FBM urolithiasis can occur, and possible contributory factors include high felbamate dosage, drug polypharmacy, and risk factors for forming stones of other types. FBM urolithiasis may be heralded by crystalluria.

Original languageEnglish (US)
Pages (from-to)682-685
Number of pages4
JournalEpilepsia
Volume42
Issue number5
DOIs
StatePublished - 2001

Fingerprint

felbamate
Urolithiasis
Stents
Urinary Bladder Calculi
Polypharmacy
Ureteral Obstruction
Cystoscopy
Urinary Retention
Lithotripsy
Urography
Hematuria
Gas Chromatography-Mass Spectrometry
Ultrasonography
Spectrum Analysis
Tomography

Keywords

  • Adverse drug event
  • Crystalluria
  • Drug urolithiasis
  • Felbamate

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Felbamate urolithiasis. / Sparagana, S. P.; Strand, W. R.; Adams, R. C.

In: Epilepsia, Vol. 42, No. 5, 2001, p. 682-685.

Research output: Contribution to journalArticle

Sparagana, S. P. ; Strand, W. R. ; Adams, R. C. / Felbamate urolithiasis. In: Epilepsia. 2001 ; Vol. 42, No. 5. pp. 682-685.
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