@article{9a4d2af35db84750a3ccb21c560fd3ff,
title = "Ferroptosis becomes immunogenic: implications for anticancer treatments",
abstract = "Ferroptosis is an iron-dependent form of non-apoptotic cell death that has recently been attributed with antitumor immune effects. Thus, early ferroptotic cells underwent immunogenic cell death that was accompanied by the emission of damage-associated molecular patterns (DAMPs) and triggered dendritic cell maturation in vitro. Furthermore, ferroptotic cells were able to vaccinate against a rechallenge with fibrosarcoma in preclinical models.",
keywords = "Damage-associated molecular pattern, anticancer vaccination, dendritic cells",
author = "Daolin Tang and Oliver Kepp and Guido Kroemer",
note = "Funding Information: GK is supported by the Ligue contre le Cancer (?quipe labellis?e); Agence National de la Recherche (ANR)?Projets blancs; ANR under the frame of E-Rare-2, the ERA-Net for Research on Rare Diseases; AMMICa US23/CNRS UMS3655; Association pour la recherche sur le cancer (ARC); Association ?Ruban Rose?; Canc?rop?le Ile-de-France; Chancelerie des universit?s de Paris (Legs Poix), Fondation pour la Recherche M?dicale (FRM); a donation by Elior; European Research Area Network on Cardiovascular Diseases (ERA-CVD, MINOTAUR); Gustave Roussy Odyssea, the European Union Horizon 2020 Project Oncobiome; Fondation Carrefour; High-end Foreign Expert Program in China (GDW20171100085), Institut National du Cancer (INCa); Inserm (HTE); Institut Universitaire de France; LeDucq Foundation; the LabEx Immuno-Oncology (ANR-18-IDEX-0001); the RHU Torino Lumi?re; the Seerave Foundation; the SIRIC Stratified Oncology Cell DNA Repair and Tumor Immune Elimination (SOCRATE); and the SIRIC Cancer Research and Personalized Medicine (CARPEM). OK is supported by the DIM Elicit. This study contributes to the IdEx Universit? de Paris ANR-18-IDEX-0001. Publisher Copyright: {\textcopyright} 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.",
year = "2021",
doi = "10.1080/2162402X.2020.1862949",
language = "English (US)",
volume = "10",
journal = "OncoImmunology",
issn = "2162-4011",
publisher = "Landes Bioscience",
number = "1",
}