Fetal hypokinesia syndrome in the monochorionic pair of a triplet pregnancy secondary to severe disruptive cerebral injury

J. M. Perlman, D. K. Burns, D. M. Twickler, A. G. Weinberg

Research output: Contribution to journalArticle

14 Scopus citations

Abstract

We report a set of triplets, two of whom were monochorionic diamnionic and demonstrated cerebellar hypoplasia and progressive arthrogryposis on an antenatal sonogram. At delivery the infants exhibited a Pena-Shokier phenotype. At autopsy, the twins were concordant for severe disruptive lesions of the cerebrum. The mechanism resulting in the devastating symmetric lesions may have been a transient cerebral vascular compromise associated with placenta vascular anastomoses characteristic of monochorionic twinning. This report accentuates the vulnerability of the monochorionic twin for ischemic cerebral injury.

Original languageEnglish (US)
Pages (from-to)521-523
Number of pages3
JournalPediatrics
Volume96
Issue number3 I
StatePublished - Jan 1 1995

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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