Fetal plasma prolactin levels

A. J. Winters, C. Colston, P. C. MacDonald, J. C. Porter

Research output: Contribution to journalArticlepeer-review

97 Scopus citations


Prolactin levels were measured by radioimmunoassay in umbilical cord plasma from fetuses, in capillary plasma from neonates, and in venous plasma from adults. The concentrations oi prolactin in cord plasma from fetuses having gestational ages of 16 to 19 weeks, 20 to 34 weeks, and 35 to 42 weeks were 53 ± 16 (mean and SE), 233 ± 30 and 371 ± 7 ng/ml, respectively. The prolactin levels decreased to 218 ± 35 ng/ml during the first neonatal week. The similarity of the patterns of prolactin levels, reported gestational estrogen levels and adrenal weights, as well as the known biological properties of prolactin, estrogen, and ACTH is consistent with the view that these three factors may be involved in the growth of the fetal adrenal cortex and its involution in the newborn.

Original languageEnglish (US)
Pages (from-to)626-629
Number of pages4
JournalJournal of Clinical Endocrinology and Metabolism
Issue number2
StatePublished - Sep 1975

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Endocrinology
  • Clinical Biochemistry
  • Biochemistry, medical

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