Fibroblast mechanics in three-dimensional collagen matrices

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Fascia provides mechanical support and frameworks for the other tissues of the body. Type 1 collagen is the major protein component of fascia, and fibroblasts are the cell type primarily responsible for its biosynthesis and remodeling. Research on fibroblasts interacting with collagen matrices provides new insights regarding how cell-matrix tension state and growth factor specificity regulate cell migration and matrix remodeling.

Original languageEnglish (US)
Pages (from-to)191-193
Number of pages3
JournalJournal of Bodywork and Movement Therapies
Volume12
Issue number3
DOIs
StatePublished - Jul 1 2008

Keywords

  • Contraction
  • Fascia
  • Growth factor
  • Migration
  • Regulation
  • Tension

ASJC Scopus subject areas

  • Complementary and Manual Therapy
  • Physical Therapy, Sports Therapy and Rehabilitation
  • Rehabilitation
  • Complementary and alternative medicine

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